M
Martin Gorges
Researcher at University of Ulm
Publications - 70
Citations - 1530
Martin Gorges is an academic researcher from University of Ulm. The author has contributed to research in topics: Amyotrophic lateral sclerosis & Default mode network. The author has an hindex of 21, co-authored 68 publications receiving 1158 citations. Previous affiliations of Martin Gorges include Gdańsk Medical University.
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Journal ArticleDOI
Neurofilament light chain in serum for the diagnosis of amyotrophic lateral sclerosis
Federico Verde,Petra Steinacker,Jochen H. Weishaupt,Jan Kassubek,Patrick Oeckl,Steffen Halbgebauer,Hayrettin Tumani,Christine A. F. von Arnim,Johannes Dorst,Emily Feneberg,Benjamin Mayer,Hans-Peter Müller,Martin Gorges,Angela Rosenbohm,Alexander E Volk,Vincenzo Silani,Albert C. Ludolph,Markus Otto +17 more
TL;DR: Serum NFL is increased in ALS in comparison to other conditions and can serve as diagnostic and prognostic biomarker and establish a cut-off level for the diagnosis of ALS.
Journal ArticleDOI
To rise and to fall: functional connectivity in cognitively normal and cognitively impaired patients with Parkinson's disease
Martin Gorges,Hans-Peter Müller,Dorothée Lulé,Elmar H. Pinkhardt,Albert C. Ludolph,Jan Kassubek +5 more
TL;DR: The increased iFC might be the initial manifestation of altered brain function preceding cognitive deficits within PD-related pathology, and could be an adaptive (compensatory) mechanism by recruiting additional resources to maintain normal cognitive performance.
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Hypothalamic atrophy is related to body mass index and age at onset in amyotrophic lateral sclerosis.
Martin Gorges,Pauline Vercruysse,Hans-Peter Müller,Hans-Jürgen Huppertz,Angela Rosenbohm,Gabriele Nagel,Patrick Weydt,Åsa Petersén,Albert C. Ludolph,Jan Kassubek,Luc Dupuis +10 more
TL;DR: Hypothalamus is atrophied in ALS, even in premorbid stages, and correlates with BMI, especially in fALS, and decreased anterior hypothalamic volume is associated with earlier onset of disease.
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Imaging the pathoanatomy of amyotrophic lateral sclerosis in vivo: targeting a propagation-based biological marker
Jan Kassubek,Hans-Peter Müller,Kelly Del Tredici,Dorothée Lulé,Martin Gorges,Heiko Braak,Albert C. Ludolph +6 more
TL;DR: The DTI-based protocol was able to image the disease patterns of ALS in vivo cross-sectionally and longitudinally, in support of DTI as a technical marker to image ALS stages.
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Functional Connectivity Mapping in the Animal Model: Principles and Applications of Resting-State fMRI
Martin Gorges,Francesco Roselli,Hans-Peter Müller,Albert C. Ludolph,Volker Rasche,Jan Kassubek +5 more
TL;DR: The longer term goal of integrating fMRI connectivity data with structural connectomes obtained with tracing and optical imaging approaches is presented and will allow the interrogation of fMRI data in terms of directional flow of information and may identify the structural underpinnings of observed functional connectivity patterns.