Martin J. Blaser

TL;DR: The mechanisms by which this slow bacterial pathogen survives and interacts with the host immune system may provide a model for other persistent mucosal pathogens.

TL;DR: The results obtained suggest that urease activity does not play a significant role in inducing the observed gastric damage, cytotoxin has an important role in the induction of gastric epithelial cell lesions but not in eliciting inflammation, and other components present in strains which carry the cagA gene, but distinct from CagA itself, are involved in elicging the inflammatory response.

TL;DR: H. pylori density in vivo is easily quantified and is associated with bacterial virulence determinants, gastric inflammation, and duodenal ulceration, suggesting a central role in pathogenesis.

TL;DR: The hypothesis that colonization with CagA+ H. pylori strains is inversely associated with asthma and is associated with an older age of asthma onset in an urban population is consistent with the hypothesis.

TL;DR: Caesarean delivery is associated with increased body mass in childhood and adolescence, and when the sample was stratified by maternal pre-pregnancy weight, the association among children born of overweight/obese mothers was strong and long-lasting.