M
Martin J. Blaser
Researcher at Center for Advanced Biotechnology and Medicine
Publications - 841
Citations - 114575
Martin J. Blaser is an academic researcher from Center for Advanced Biotechnology and Medicine. The author has contributed to research in topics: Helicobacter pylori & CagA. The author has an hindex of 147, co-authored 820 publications receiving 104104 citations. Previous affiliations of Martin J. Blaser include Nagoya University & University of Maryland, Baltimore.
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Journal ArticleDOI
The effect of H. pylori eradication on meal-associated changes in plasma ghrelin and leptin
Fritz Francois,Fritz Francois,Jatin Roper,Neal Joseph,Zhiheng Pei,Zhiheng Pei,Aditi Chhada,Joshua R. Shak,Asalia Z. Olivares de Perez,Guillermo I. Perez-Perez,Martin J. Blaser,Martin J. Blaser +11 more
TL;DR: Circulating meal-associated leptin and ghrelin levels and BMI changed significantly after H. pylori eradication, providing direct evidence that H.pylori colonization is involved in gh Relin and leptin regulation, with consequent effects on body morphometry.
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Experimental Campylobacter jejuni infection in Macaca nemestrina.
TL;DR: The results demonstrate that C. jejuni infection in M. nemestrina caused colitis with clinical and pathologic results similar to those found in humans and indicate that prior infection protects against subsequent challenge.
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Distinct cutaneous bacterial assemblages in a sampling of South American Amerindians and US residents
Martin J. Blaser,Maria Gloria Dominguez-Bello,Monica Contreras,Magda Magris,Glida Hidalgo,Isidoro Estrada,Zhan Gao,Jose C. Clemente,Elizabeth K. Costello,Rob Knight,Rob Knight +10 more
TL;DR: Evidence is provided that ethnicity, lifestyle and/or geography are associated with the structure of human cutaneous bacterial communities, including Proteobacteria and Firmicutes, in Amerindians in the Venezuelan Amazon.
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Effect of Helicobacter pylori products and recombinant cytokines on gastrin release from cultured canine G cells
I. L. P. Beales,Martin J. Blaser,S Srinivasan,John Calam,Guillermo I. Perez-Perez,Thoru Yamada,James M. Scheiman,L Post,J. Del Valle +8 more
TL;DR: IL-8 stimulated gastrin release from isolated G cells, and the effect was potentiated by H. pylori products, which may contribute to the hypergastrinemia seen in vivo.
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Apoptosis in gastric epithelial cells is induced by Helicobacter pylori and accompanied by increased expression of BAK.
Guo-Qiang Chen,Emilia Mia Sordillo,William G. Ramey,J. Reidy,Peter R. Holt,Stan Krajewski,John C. Reed,Martin J. Blaser,Steven F. Moss +8 more
TL;DR: The induction of apoptosis by H. pylori was time and concentration-dependent and inhibited by preventing direct bacterial-epithelial cell contact, and was accompanied by increased expression of Bak, with little change in expression of other Bcl-2 family proteins.