M
Martin J. Blaser
Researcher at Center for Advanced Biotechnology and Medicine
Publications - 841
Citations - 114575
Martin J. Blaser is an academic researcher from Center for Advanced Biotechnology and Medicine. The author has contributed to research in topics: Helicobacter pylori & CagA. The author has an hindex of 147, co-authored 820 publications receiving 104104 citations. Previous affiliations of Martin J. Blaser include Nagoya University & University of Maryland, Baltimore.
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DNA sequence conservation and diversity in transposable element IS605 of Helicobacter pylori.
Johanna Höök-Nikanne,Douglas E. Berg,Richard M. Peek,Dange Kersulyte,Murali K. R. Tummuru,Martin J. Blaser +5 more
TL;DR: A transposable element‐like sequence identified in the virulence‐associated cag region of Helicobacter pylori reference strain NCTC11638 is unusual in containing two oppositely‐oriented open reading frames whose products are homologues of the single transposases of the unrelated elements, IS200 and IS1341.
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Salmonellosis at rural and urban clinics in bangladesh epidemiologic and clinical characteristics
TL;DR: Patients with diarrheal illness associated with isolation of Salmonella frequency had vomiting, watery diarrhea, abdominal pain, and fever, but the clinical features of the illnesses and the socioeconomic backgrounds of the patients could not be distinguished from those of matched controls who were attending the same clinic.
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Regulatory opportunities to encourage technology solutions to antibacterial drug resistance
Roger Finch,Martin J. Blaser,Otto Carrs,Gail Cassell,Neil Fishman,Robert Guidos,Stuart Levy,John H. Powers,Ragnar Norrby,Glenn Tillotson,Rick Davies,Steven J. Projan,Michael J. Dawson,Dominique Monnet,Marcus Keogh-Brown,Kieran Hand,Sarah Garner,David Findlay,Chantal M. Morel,Richard Wise,Richard Bax,Frances Burke,Ian Chopra,Lloyd Czaplewski,David M. Livermore,Laura J. V. Piddock,Tony White +26 more
TL;DR: The 'Urgent Need' Working Party to address the regeneration of antibacterial drug discovery and development identified a number of issues, including increased application of pharmacokinetic/pharmacodynamic principles to expedite drug development; the need to prioritize licensing of drugs active in life-threatening infections; and expansion of the use of surrogate markers and rapid point of care diagnostics to facilitate drug development.
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Effect of antibiotic pre-treatment and pathogen challenge on the intestinal microbiota in mice.
Tadasu Iizumi,Takako Taniguchi,Wataru Yamazaki,Geraldine Vilmen,Alexander V. Alekseyenko,Zhan Gao,Guillermo I. Perez Perez,Martin J. Blaser +7 more
TL;DR: It is concluded that despite gut microbiota disturbance, susceptibility to gut colonization by these pathogens was unchanged and the major gut microbiome disturbance produced by antibiotic treatment may be reduced by colonization with specific microbial taxa.
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Surveillance for the detection of nesocomial infections and the potential for nesocomial outbreaks I. Microbiology culture surveillance is an effective method of detecting nosocomial infection
TL;DR: A study to determine the sensitivity and specificity of a laboratory-based surveillance system using numbers of positive cultures in a medical-surgical patient charts found that 48% represented nosocomial infections.