M
Martin J. Blaser
Researcher at Center for Advanced Biotechnology and Medicine
Publications - 841
Citations - 114575
Martin J. Blaser is an academic researcher from Center for Advanced Biotechnology and Medicine. The author has contributed to research in topics: Helicobacter pylori & CagA. The author has an hindex of 147, co-authored 820 publications receiving 104104 citations. Previous affiliations of Martin J. Blaser include Nagoya University & University of Maryland, Baltimore.
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Journal ArticleDOI
Cure of Helicobacter pylori infection by omeprazole-clarithromycin-based therapy in non-human primates.
Andre Dubois,Douglas E. Berg,Nancy Fiala,Lillie M. Heman-Ackah,Guillermo I. Perez-Perez,Martin J. Blaser +5 more
TL;DR: Results indicate that an omeprazole-clarithromycin-omepazole-based regimen can cure H. pylori infection in Rhesus monkeys, with resolution of abnormal histology and serologic responses, and suggest that this preclinical animal model is useful for testing new anti-H.pylori therapies.
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Detection of anti-VacA antibody responses in serum and gastric juice samples using type s1/m1 and s2/m2 Helicobacter pylori VacA antigens.
Guillermo I. Perez-Perez,Richard M. Peek,John Atherton,Martin J. Blaser,Martin J. Blaser,Timothy L. Cover,Timothy L. Cover +6 more
TL;DR: Data indicate that different VacA isoforms have distinct antigenic properties and that multiple forms of VacA elicit antibody responses in H. pylori-positive humans.
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Intergenerational reduction in Helicobacter pylori prevalence is similar between different ethnic groups living in a Western city
Wouter den Hollander,I. Lisanne Holster,Bianca van Gilst,Anneke J van Vuuren,Vincent W. V. Jaddoe,Albert Hofman,Guillermo I. Perez-Perez,Ernst J. Kuipers,Henriëtte A. Moll,Martin J. Blaser +9 more
TL;DR: Although the highest H. pylori and CagA prevalence was found in children of non-Dutch ethnicities, the decreased colonisation rates were uniform across all ethnic groups, implying the importance of environmental factors in H. Pylori transmission in modern cities, independent of ethnicity.
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The role of the changing human microbiome in the asthma pandemic.
TL;DR: The focus of this review is to highlight the strides the field has made in characterizing the constituents of the human gastrointestinal microbiota, such as Helicobacter pylori, other members of the neonatal intestinal microbiota, and microbial peptides and metabolites that influence host immunity and immune response to allergens.
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Production of a Shiga-like cytotoxin by Campylobacter
TL;DR: The data indicate that low levels of Shiga-like toxin are produced by some Campylobacter isolates but that SLT is genetically distinct from the SLT-I toxin produced at high levels by certain E. coli strains.