M
Martin Picard
Researcher at University of Paris
Publications - 34
Citations - 1394
Martin Picard is an academic researcher from University of Paris. The author has contributed to research in topics: ATPase & Membrane protein. The author has an hindex of 17, co-authored 34 publications receiving 1197 citations. Previous affiliations of Martin Picard include University of Paris-Sud & Centre national de la recherche scientifique.
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Journal ArticleDOI
The structural basis of calcium transport by the calcium pump
Claus Olesen,Martin Picard,Martin Picard,Anne-Marie Lund Winther,Anne-Marie Lund Winther,Claus Gyrup,J. Preben Morth,J. Preben Morth,Claus Oxvig,Jesper V. Møller,Jesper V. Møller,Poul Nissen,Poul Nissen +12 more
TL;DR: Functional studies and three new crystal structures of the rabbit skeletal muscle Ca2+-ATPase are presented, representing the phosphoenzyme intermediates associated withCa2+ binding, Ca2- translocation and dephosphorylation, that are based on complexes with a functional ATP analogue, beryllium fluoride and aluminium fluoride, respectively.
Journal ArticleDOI
Tripartite assembly of RND multidrug efflux pumps.
Laetitia Daury,François Orange,François Orange,Jean-Christophe Taveau,Jean-Christophe Taveau,Alice Verchère,Laura Monlezun,Céline Gounou,Céline Gounou,Ravi K. R. Marreddy,Martin Picard,Isabelle Broutin,Klaas M. Pos,Olivier Lambert,Olivier Lambert +14 more
TL;DR: The reconstitution of native Pseudomonas aeruginosa MexAB–OprM and Escherichia coli AcrAB–TolC tripartite Resistance Nodulation and cell Division (RND) efflux systems in a lipid nanodisc system is presented.
Journal ArticleDOI
Protective and inhibitory effects of various types of amphipols on the Ca2+-ATPase from sarcoplasmic reticulum: a comparative study.
Martin Picard,Tassadite Dahmane,Manuel Garrigos,Carole Gauron,Fabrice Giusti,Marc le Maire,Jean-Luc Popot,Philippe Champeil +7 more
TL;DR: It is shown here that aggregation can be prevented by omitting calcium from buffers or by using a sulfonated version of A8-35, and that the other three amphipol tested also display these properties and that all four amphipols slow down backward calcium dissociation from the nonphosphorylated solubilized enzyme, a priori an unrelated step.
Journal ArticleDOI
Structure, Assembly, and Function of Tripartite Efflux and Type 1 Secretion Systems in Gram-Negative Bacteria
Ilyas Alav,Jessica Kobylka,Miriam S. Kuth,Klaas M. Pos,Martin Picard,Jessica M A Blair,Vassiliy N. Bavro +6 more
TL;DR: In this article, the authors summarize the recent advances in understanding of structural biology, function, and regulation of these systems, highlighting the previously undescribed role of periplasmic adaptor proteins (PAPs) in providing a common architectural scaffold across diverse families of transporters.
Journal ArticleDOI
Quantification of Detergents Complexed with Membrane Proteins
Vincent Chaptal,Frédéric Delolme,Arnaud Kilburg,Sandrine Magnard,Cédric Montigny,Martin Picard,Charlène Prier,Luca Monticelli,Olivier Bornert,Morgane Agez,Stéphanie Ravaud,Cédric Orelle,Renaud Wagner,Anass Jawhari,Isabelle Broutin,Eva Pebay-Peyroula,Jean-Michel Jault,H. Ronald Kaback,Marc le Maire,Pierre Falson +19 more
TL;DR: A method based on matrix-assisted laser desorption/ionization mass spectrometry (MALDI-TOF MS) that allows quantification of pure or mixed detergents in complex with membrane proteins, and validated the method with a wide variety of deterGents and membrane proteins.