M
Martin von Bergen
Researcher at Helmholtz Centre for Environmental Research - UFZ
Publications - 395
Citations - 19405
Martin von Bergen is an academic researcher from Helmholtz Centre for Environmental Research - UFZ. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 58, co-authored 346 publications receiving 15305 citations. Previous affiliations of Martin von Bergen include Max Planck Society & Leipzig University.
Papers
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Journal ArticleDOI
The Activation of Mucosal-Associated Invariant T (MAIT) Cells Is Affected by Microbial Diversity and Riboflavin Utilization in vitro.
Jannike Lea Krause,Stephanie Serena Schäpe,Florian Schattenberg,Susann Müller,Grit Ackermann,Ulrike Rolle-Kampczyk,Nico Jehmlich,Arkadiusz Pierzchalski,Martin von Bergen,Martin von Bergen,Gunda Herberth +10 more
TL;DR: It is shown that MAIT cells can perceive microbial stress due to changes in riboflavin utilization and that rib oflavin availability might also play a central role for the MAIT cell activating potential of diverse microbiota.
Journal ArticleDOI
Differential cellular metabolite alterations in HaCaT cells caused by exposure to the aryl hydrocarbon receptor-binding polycyclic aromatic hydrocarbons chrysene, benzo[a]pyrene and dibenzo[a,l]pyrene.
Sarah Potratz,Harald Jungnickel,Stefan Grabiger,Patrick Tarnow,Wolfgang Otto,Ellen Fritsche,Martin von Bergen,Andreas Luch +7 more
TL;DR: The results suggest that in vitro metabolomics can serve as tool to develop bioassays for application in hazard assessment, and up-regulation of sphingomyelin levels after exposure to BAP and DALP point to pro-apoptotic processes caused by these two potent PAHs.
Journal ArticleDOI
The effect of a high-polyphenol Mediterranean diet (Green-MED) combined with physical activity on age-related brain atrophy: the Dietary Intervention Randomized Controlled Trial Polyphenols Unprocessed Study (DIRECT PLUS)
Alon Kaplan,Hila Zelicha,Anat Yaskolka Meir,Ehud Rinott,Gal Tsaban,Gidon Levakov,Ofer Prager,Moti Salti,Yoram Yovell,Jonathan Ofer,Sebastian Huhn,Frauke Beyer,A. Veronica Witte,Arno Villringer,Nachshon Meiran,T Emesh,Peter Kovacs,Martin von Bergen,Uta Ceglarek,Matthias Blüher,Michael Stumvoll,Frank B. Hu,Meir J. Stampfer,Alon Friedman,Ilan Shelef,Galia Avidan,Iris Shai +26 more
TL;DR: A Green-MED (high-polyphenol) diet, rich in Mankai, green tea, and walnuts and low in red/processed meat, is potentially neuroprotective for age-related brain atrophy.
Journal ArticleDOI
High metabolic in vivo stability and bioavailability of a palmitoylated ghrelin receptor ligand assessed by mass spectrometry.
Katja B. Kostelnik,Sylvia Els-Heindl,Nora Klöting,Sven Baumann,Martin von Bergen,Annette G. Beck-Sickinger +5 more
TL;DR: In-depth structure-activity relationship studies revealed a palmitoylated ghrelin receptor ligand that displays an in vitro binding affinity in the low nanomolar range and in vitro metabolic analysis indicated a high stability in blood serum and liver homogenate.
Patent
Screening for inhibitors of 'paired helical filaments'
TL;DR: In this paper, a method for identifying and obtaining an inhibitor capable of modifying the PHF formation is presented, which can be used to detect the presence, decrease, or absence of nucleation sites for PHF assembly.