M
Martin von Bergen
Researcher at Helmholtz Centre for Environmental Research - UFZ
Publications - 395
Citations - 19405
Martin von Bergen is an academic researcher from Helmholtz Centre for Environmental Research - UFZ. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 58, co-authored 346 publications receiving 15305 citations. Previous affiliations of Martin von Bergen include Max Planck Society & Leipzig University.
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Journal ArticleDOI
Subtoxic and toxic concentrations of benzene and toluene induce Nrf2-mediated antioxidative stress response and affect the central carbon metabolism in lung epithelial cells A549
Kalaimathi Murugesan,Sven Baumann,Dirk K. Wissenbach,Stefanie Kliemt,Stefan Kalkhof,Wolfgang Otto,Iljana Mögel,Tibor Kohajda,Martin von Bergen,Martin von Bergen,Janina M. Tomm +10 more
TL;DR: The molecular alterations identified as a result of benzene and toluene exposure demonstrate the detrimental effect of nonacute toxic concentrations on lung epithelial cells.
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Autoproteolytic stability of a trypsin from the marine crab Cancer pagurus.
Jan-Hendrik Hehemann,Lars Redecke,Jayaseelan Murugaiyan,Martin von Bergen,Christian Betzel,Reinhard Saborowski +5 more
TL;DR: It is shown by characterisation of a novel trypsin from the gastric fluid of the marine crab Cancer pagurus that this property might be assigned to the entire class of crustaceans, and the high resistance against autoproteolysis was determined by mass spectrometry.
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Subpopulation-proteomics reveal growth rate, but not cell cycling, as a major impact on protein composition in Pseudomonas putida KT2440
Sarah Lieder,Michael Jahn,Jana Seifert,Jana Seifert,Martin von Bergen,Martin von Bergen,Susann Müller,Ralf Takors +7 more
TL;DR: Cells in various cell cycle stages at the same growth rate were found to have similar to identical proteome profiles showing no significant population heterogeneity on the proteome level, as the growth rate clearly determines the protein composition and therefore the metabolic strategy of the cells.
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25‐Hydroxyvitamin D3 Synthesis by Enzymatic Steroid Side‐Chain Hydroxylation with Water
Markus Warnke,Tobias Jung,Juri Dermer,Karin Hipp,Nico Jehmlich,Martin von Bergen,Sascha Ferlaino,Alexander Fries,Michael Müller,Matthias Boll +9 more
TL;DR: This facile and robust method developed for 25OHVD3 synthesis is a novel example for the concept of substrate-engineered catalysis and offers an attractive alternative to chemical or O2 /electron-donor-dependent enzymatic procedures.
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DIGE-based protein expression analysis of B[a]P-exposed hepatoma cells reveals a complex stress response including alterations in oxidative stress, cell cycle control, and cytoskeleton motility at toxic and subacute concentrations.
Franziska Dautel,Stefan Kalkhof,Saskia Trump,Jacob J. Michaelson,Andreas Beyer,Irina Lehmann,Martin von Bergen +6 more
TL;DR: It is demonstrated that B[a]P exposure alters the cellular response by disturbing proteins involved in oxidative stress, cell cycle regulation, apoptosis, and cytoskeleton organization by triggering an immediate response to the contaminant at the protein level.