Mary A. Foulkes

TL;DR: Over 10 years, from a payer perspective, lifestyle was cost-effective and metformin was marginally cost-saving compared with placebo.

TL;DR: Of the several recognized histologic patterns, the filagree pattern--an organoid pattern consisting of bicellular strands of tissue separated by filmy vascular stroma--was associated with the lowest survival rates, and the most important predictor of clinical behavior, regardless of treatment modality, was the site of primary involvement.

TL;DR: The gnathic bones were commonly affected, yet there was no associated mortality; no patient with primary disease in the bones of the head and neck who survived for 5 years on any of the IESS protocols has subsequently died.

TL;DR: The overall similarity of the microbiomes in participants with and without HIV infection was unexpected, because HIV-infected individuals with relatively preserved CD4 cell counts are at higher risk for lower respiratory tract infections, indicating impaired local immune function.

TL;DR: No significant difference in median survival could be detected in patients with pelvic primaries between regimens I, II and III and the possible reasons for the poor prognosis of pelvic primary patients are discussed together with treatment policies that might improve the survival of this group of patients.