M
Mary C. Clark
Researcher at University of California, Los Angeles
Publications - 11
Citations - 537
Mary C. Clark is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 5, co-authored 5 publications receiving 484 citations. Previous affiliations of Mary C. Clark include Cedars-Sinai Medical Center.
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Journal ArticleDOI
HMGB1 Mediates Endogenous TLR2 Activation and Brain Tumor Regression
James F. Curtin,James F. Curtin,Naiyou Liu,Naiyou Liu,Marianela Candolfi,Marianela Candolfi,Weidong Xiong,Weidong Xiong,Hikmat Assi,Hikmat Assi,Kader Yagiz,Kader Yagiz,Matthew R. Edwards,Kathrin S. Michelsen,Kurt M. Kroeger,Kurt M. Kroeger,Chunyan Liu,Chunyan Liu,A.K.M. Ghulam Muhammad,A.K.M. Ghulam Muhammad,Mary C. Clark,Mary C. Clark,Moshe Arditi,Begonya Comin-Anduix,Antoni Ribas,Pedro R. Lowenstein,Maria G. Castro +26 more
TL;DR: Evidence is provided for the molecular and cellular mechanisms that support the rationale for the clinical implementation of antibrain cancer immunotherapies in combination with tumor killing approaches in order to elicit effective antitumor immune responses, and thus, will impact clinical neuro-oncology practice.
Journal ArticleDOI
Galectin-3 binds to CD45 on diffuse large B-cell lymphoma cells to regulate susceptibility to cell death.
Mary C. Clark,Mabel Pang,Daniel K. Hsu,Fu-Tong Liu,Sven de Vos,Randy D. Gascoyne,Jonathan W. Said,Linda G. Baum +7 more
TL;DR: A novel role for cell-surface gal-3 and CD45 in DLBCL survival is identified and novel therapeutic targets to sensitizeDLBCL cells to death are suggested.
Journal ArticleDOI
T cells modulate glycans on CD43 and CD45 during development and activation, signal regulation, and survival.
Mary C. Clark,Linda G. Baum +1 more
TL;DR: This review focuses on changes in glycosylation of CD43 and CD45 occurring throughout T cell development and activation and the role that gly cosylation plays in regulating T cell processes, such as migration, T cell receptor signaling, and apoptosis.
Journal ArticleDOI
The neurogenetics of atypical parkinsonian disorders.
TL;DR: The wide range of phenotypes observed from mutations in a single gene warrants broad testing facilitated by advances in DNA sequencing, and expanding genomic approaches, ranging from the use of next-generation sequencing to identify causative or risk-associated gene variations to the study of epigenetic modification, are poised to lead the field into a new age of discovery.