M
Masamichi Takami
Researcher at Showa University
Publications - 108
Citations - 5406
Masamichi Takami is an academic researcher from Showa University. The author has contributed to research in topics: Osteoclast & RANKL. The author has an hindex of 31, co-authored 103 publications receiving 4978 citations. Previous affiliations of Masamichi Takami include Nippon Steel & Tokyo Institute of Technology.
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Journal ArticleDOI
Nephronectin expression is regulated by SMAD signaling in osteoblast-like MC3T3-E1 cells.
Masayuki Tsukasaki,Atsushi Yamada,Kentaro Yoshimura,Agasa Miyazono,Matsuo Yamamoto,Masamichi Takami,Yoichi Miyamoto,Naoko Morimura,Ryutaro Kamijo +8 more
TL;DR: In this study, inhibition of a TGF-β type I receptor by a specific inhibitor strongly induced Npnt expression in osteoblast-like MC3T3-E1 cells, suggesting that the expression of NpNT is regulated by the Alk5-SMAD signaling pathway in osteoblasts.
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Myelination during fracture healing in vivo in myelin protein zero (p0) transgenic medaka line.
Yusuke Dodo,Masahiro Chatani,Yuki Azetsu,Masahiro Hosonuma,Akiko Karakawa,Nobuhiro Sakai,Takako Negishi-Koga,Mayumi Tsuji,Katsunori Inagaki,Yuji Kiuchi,Masamichi Takami +10 more
TL;DR: The findings indicated that mTOR signaling plays important roles in bone formation and neural networking during fracture healing, and the first to show the dynamics of myelinating cells in vivo.
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Down-regulation of Irf8 by Lyz2-cre/loxP accelerates osteoclast differentiation in vitro
Emi Saito,Dai Suzuki,Daisuke Kurotaki,Ayako Mochizuki,Yoko Manome,Tetsuo Suzawa,Yoichi Toyoshima,Takahiro Ichikawa,Takahiro Funatsu,Tomio Inoue,Masamichi Takami,Tomohiko Tamura,Katsunori Inagaki,Ryutaro Kamijo +13 more
TL;DR: The existence in vivo of a new lineage of osteoclast precursors among BMCs, which differentiate into osteoclasts without up-regulation of Lyz2 expression is proposed.
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Biological Effects of Anti-RANKL Antibody and Zoledronic Acid on Growth and Tooth Eruption in Growing Mice.
Motoki Isawa,Akiko Karakawa,Nobuhiro Sakai,Saki Nishina,Miku Kuritani,Masahiro Chatani,Takako Negishi-Koga,Takako Negishi-Koga,Masashi Sato,Mitsuko Inoue,Yukie Shimada,Masamichi Takami +11 more
TL;DR: Findings suggest regulation of tooth eruption via osteoblast differentiation by some types of anti-resorptive drugs by affecting body growth, tooth root formation, and tooth eruption in growing children.
Journal ArticleDOI
Differentiation and function of osteoclasts cultured on bone and cartilage.
TL;DR: It is suggested that, even on uncalcified substrata, the terminal differentiation of BMM into functional OC is induced by an unidentified external stimulus, which may be contained in the cell membrane of yeast particles.