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Melissa Dullaers
Researcher at Baylor University
Publications - 11
Citations - 1809
Melissa Dullaers is an academic researcher from Baylor University. The author has contributed to research in topics: T cell & Interleukin 21. The author has an hindex of 7, co-authored 9 publications receiving 1542 citations. Previous affiliations of Melissa Dullaers include Baylor University Medical Center & French Institute of Health and Medical Research.
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Journal ArticleDOI
Human Blood CXCR5+CD4+ T Cells Are Counterparts of T Follicular Cells and Contain Specific Subsets that Differentially Support Antibody Secretion
Rimpei Morita,Nathalie Schmitt,Salah Eddine Bentebibel,Rajaram Ranganathan,Laure Bourdery,Gerard Zurawski,Gerard Zurawski,Emile Foucat,Melissa Dullaers,Sangkon Oh,Sangkon Oh,Natalie Sabzghabaei,Elizabeth M. Lavecchio,Marilynn Punaro,Marilynn Punaro,Virginia Pascual,Virginia Pascual,Jacques Banchereau,Jacques Banchereau,Jacques Banchereau,Hideki Ueno,Hideki Ueno +21 more
TL;DR: In this article, human blood CXCR5(+)CD4(+) T cells share functional properties with T follicular helper (Tfh) cells and appear to represent their circulating memory compartment.
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Targeting self- and foreign antigens to dendritic cells via DC-ASGPR generates IL-10–producing suppressive CD4+ T cells
Dapeng Li,Gabrielle Romain,Anne-Laure Flamar,Dorothée Duluc,Melissa Dullaers,Xiao Hua Li,Sandra Zurawski,Nathalie Bosquet,Anna Karolina Palucka,Anna Karolina Palucka,Roger Le Grand,Anne O'Garra,Gerard Zurawski,Jacques Banchereau,Jacques Banchereau,Sangkon Oh +15 more
TL;DR: Targeting antigens to the lectinlike DC-ASGPR receptor on human DCs and in nonhuman primates results in the induction of antigen-specific IL-10–producing CD4+ T cells.
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A T cell-dependent mechanism for the induction of human mucosal homing immunoglobulin A-secreting plasmablasts.
Melissa Dullaers,Dapeng Li,Yaming Xue,Ling Ni,Ingrid Gayet,Rimpei Morita,Hideki Ueno,Karolina Palucka,Jacques Banchereau,Sangkon Oh +9 more
TL;DR: It is shown that follicular helper T cells (Tfh) contribute to mucosal IgA, and mucosal vaccines should aim to induce robust Tfh responses.
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Macrophages induce differentiation of plasma cells through CXCL10/IP-10
Wei Xu,Wei Xu,Hye Mee Joo,Sandra Clayton,Melissa Dullaers,Marie Cecile Herve,Derek M. Blankenship,Maria Teresa de la Morena,Robert S. Balderas,Capucine Picard,Jean-Laurent Casanova,Virginia Pascual,Sangkon Oh,Jacques Banchereau +13 more
TL;DR: Macrophage production of CXCL10 amplifies the production of IL-6 by B cells, leading to plasma cell differentiation in mice, and this results in differentiation of B cells intoocytes and plasma cells respectively.
Journal ArticleDOI
Functional diversity of human vaginal APC subsets in directing T-cell responses
Dorothée Duluc,Julien Gannevat,Esperanza Anguiano,Sandra Zurawski,Michael Carley,Muriel Boreham,Jack Stecher,Melissa Dullaers,Jacques Banchereau,Sangkon Oh,Sangkon Oh +10 more
TL;DR: It is demonstrated that immune responses in the vagina can be orchestrated by the functional diversity of four major antigen-presenting cell (APC) subsets, and microbial products do not bias them to elicit common types of immune responses.