M
Mengze Xu
Researcher at University of Macau
Publications - 25
Citations - 328
Mengze Xu is an academic researcher from University of Macau. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 6, co-authored 12 publications receiving 103 citations.
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Journal ArticleDOI
Phototheranostic Metal-Phenolic Networks with Antiexosomal PD-L1 Enhanced Ferroptosis for Synergistic Immunotherapy.
Lisi Xie,Jie Li,Guohao Wang,Wei Sang,Mengze Xu,Wenxi Li,Jie Yan,Bei Li,Zhan Zhang,Qi Zhao,Zhen Yuan,Quli Fan,Yu-ping Dai +12 more
TL;DR: This novel synergy of PTT with antiexosomal PD-L1 enhanced ferroptosis evoked potent antitumor immunity in B16F10 tumors and immunological memory against metastatic tumors in lymph nodes.
Journal ArticleDOI
Inhibiting tumor oxygen metabolism and simultaneously generating oxygen by intelligent upconversion nanotherapeutics for enhanced photodynamic therapy.
Dan Wang,Bin Xue,Tymish Y. Ohulchanskyy,Yubin Liu,Artem Yakovliev,Roman Ziniuk,Mengze Xu,Jun Song,Junle Qu,Zhen Yuan +9 more
TL;DR: These findings offer a promising aproach to conquer the serious hypoxia problem in cancer therapy by turning down the O2 metabolism aveneue and simultaneously generating O2.
Journal ArticleDOI
A hypoxia responsive nanoassembly for tumor specific oxygenation and enhanced sonodynamic therapy.
Kuikun Yang,Ludan Yue,Guocan Yu,Lang Rao,Rui Tian,Jianwen Wei,Zhiqing Yang,Chen Sun,Xiangjun Zhang,Mengze Xu,Zhen Yuan,Xiaoyuan Chen,Ruibing Wang +12 more
TL;DR: In this paper, a hypoxia-responsive nanovesicle (hMVs) was used as delivery vehicle of a sonosensitizer to enhance the efficacy of SDT via specific payload release and local oxygenation in the tumor.
Journal ArticleDOI
Temperature-Feedback Nanoplatform for NIR-II Penta-Modal Imaging-Guided Synergistic Photothermal Therapy and CAR-NK Immunotherapy of Lung Cancer.
Mengze Xu,Bin Xue,Yue Wang,Dan Wang,Duyang Gao,Shuo Yang,Qi Zhao,Cangtao Zhou,Shuangchen Ruan,Zhen Yuan +9 more
TL;DR: In this article, a theranostic nanoplatform that introduced upconversion nanoparticles (UCNPs) and IR-1048 dye into the lipid-aptamer nanostructrure (UCILA) is constructed.
Journal ArticleDOI
Dimeric camptothecin-loaded RGD-modified targeted cationic polypeptide-based micelles with high drug loading capacity and redox-responsive drug release capability
TL;DR: Results indicate that dimeric camptothecin-loaded cationic polypeptide-based micelle is a promising strategy for cancer therapy.