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Michael Baumann

Researcher at Helmholtz-Zentrum Dresden-Rossendorf

Publications -  94
Citations -  1879

Michael Baumann is an academic researcher from Helmholtz-Zentrum Dresden-Rossendorf. The author has contributed to research in topics: Cancer & Radiation therapy. The author has an hindex of 18, co-authored 90 publications receiving 1287 citations. Previous affiliations of Michael Baumann include German Cancer Research Center & Dresden University of Technology.

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Cancer stem cells: Radioresistance, prediction of radiotherapy outcome and specific targets for combined treatments.

TL;DR: The high heterogeneity of CSC subclones along with changes of the functional behavior of individual tumors under treatment underlines the importance of the selection of the optimal timepoint(s) of biomarker evaluation, but also provides a potential therapeutic target for combined treatment approaches with irradiation.
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Residual tumour hypoxia in head-and-neck cancer patients undergoing primary radiochemotherapy, final results of a prospective trial on repeat FMISO-PET imaging.

TL;DR: This study validates that residual tumour hypoxia during radiochemotherapy is a major driver of therapy resistance of HNSCC, and that hypoxic volume after the second week of treatment measured by FMISO-PET may serve as biomarker for selection of patients at high risk of loco-regional recurrence after state-of-the art radiochem therapy.