M
Michael D. Radmacher
Researcher at Ohio State University
Publications - 77
Citations - 13454
Michael D. Radmacher is an academic researcher from Ohio State University. The author has contributed to research in topics: Leukemia & BAALC. The author has an hindex of 40, co-authored 77 publications receiving 12921 citations. Previous affiliations of Michael D. Radmacher include Duke University & Kenyon College.
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Journal ArticleDOI
Graph models of oncogenesis with an application to melanoma.
Michael D. Radmacher,Richard M. Simon,Richard Desper,Raymond Taetle,Alejandro A. Schäffer,Mark A. Nelson +5 more
TL;DR: This study illustrates that the application of graph models to genetic data from tumor sets provide new information on the interrelationships among genetic changes during tumor progression.
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Low expression of MN1 associates with better treatment response in older patients with de novo cytogenetically normal acute myeloid leukemia
Sebastian Schwind,Guido Marcucci,Jessica Kohlschmidt,Michael D. Radmacher,Krzysztof Mrózek,Kati Maharry,Heiko Becker,Klaus H. Metzeler,Susan P. Whitman,Yue-Zhong Wu,Bayard L. Powell,Maria R. Baer,Jonathan E. Kolitz,Andrew J. Carroll,Richard A. Larson,Michael A. Caligiuri,Clara D. Bloomfield +16 more
TL;DR: It is concluded that low MN1 expression confers better prognosis in older CN-AML patients and may refine the European LeukemiaNet classification.
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MicroRNA expression in acute myeloid leukemia.
TL;DR: Genome-wide analyses of microRNA expression have revealed signatures associated with selected cytogenetic and molecular subsets of AML and have led to the recognition of previously unreported molecular pathways involved in myeloid leukemogenesis.
Journal ArticleDOI
Molecular signatures in acute myeloid leukemia
TL;DR: Gene-expression and microRNA-expression profiling not only has the potential to enhance the understanding of the disease biology, but also appears to constitute an applicable approach for outcome prediction and identification of novel therapeutic targets.
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STAT1-dependent and STAT1-independent gene expression in murine immune cells following stimulation with interferon-alpha
TL;DR: This report is the first to demonstrate that STAT1-mediated signal transduction plays a major role in the transcriptional response of murine immune cells to IFNα.