M
Michael E. Widlansky
Researcher at Medical College of Wisconsin
Publications - 91
Citations - 7806
Michael E. Widlansky is an academic researcher from Medical College of Wisconsin. The author has contributed to research in topics: Endothelial dysfunction & Endothelium. The author has an hindex of 32, co-authored 83 publications receiving 6921 citations. Previous affiliations of Michael E. Widlansky include Boston University.
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Journal ArticleDOI
The clinical implications of endothelial dysfunction.
TL;DR: This work suggests that studies of endothelial function could be used in the care of patients and as a surrogate marker for the evaluation of new therapeutic strategies, and a growing number of interventions known to reduce cardiovascular risk have been shown to improve endothelialfunction.
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Assessment of flow-mediated dilation in humans: a methodological and physiological guideline
Dick H. J. Thijssen,Mark A. Black,Mark A. Black,Kyra E. Pyke,Jaume Padilla,Greg Atkinson,Ryan A. Harris,Beth A. Parker,Michael E. Widlansky,Michael E. Tschakovsky,Daniel J. Green +10 more
TL;DR: A series of recommendations on the basis of review and critical appraisal of recent physiological studies, pertaining to the most appropriate methods to assess FMD in humans are made.
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Physical Inactivity Rapidly Induces Insulin Resistance and Microvascular Dysfunction in Healthy Volunteers
Naomi M. Hamburg,Craig J. McMackin,Alex L. Huang,Sherene M. Shenouda,Michael E. Widlansky,Eberhard Schulz,Noyan Gokce,Neil B. Ruderman,John F. Keaney,Joseph A. Vita +9 more
TL;DR: Physical inactivity was associated with the development of insulin resistance, dyslipidemia, increased blood pressure, and impaired microvascular function in healthy volunteers and may provide insight into the pathogenesis of vascular disease in sedentary individuals.
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Altered Mitochondrial Dynamics Contributes to Endothelial Dysfunction in Diabetes Mellitus
Sherene M. Shenouda,Michael E. Widlansky,Kai Chen,Guoquan Xu,Monika Holbrook,Corey E. Tabit,Naomi M. Hamburg,Alissa A. Frame,Tara L. Caiano,Matthew A. Kluge,Mai-Ann Duess,Aaron Levit,Brian H Kim,Mor-Li Hartman,Lija Joseph,Orian S. Shirihai,Joseph A. Vita +16 more
TL;DR: Findings implicate increased mitochondrial fission as a contributing mechanism for endothelial dysfunction in diabetic states through increased reactive oxygen species production.
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Lipoic acid as a potential therapy for chronic diseases associated with oxidative stress.
TL;DR: The known biochemical properties of alpha-Lipoic acid are reviewed with particular reference to how LA may be an effective agent to ameliorate certain pathophysiologies of many chronic diseases.