M
Michael G. Neubauer
Researcher at Bristol-Myers Squibb
Publications - 42
Citations - 5566
Michael G. Neubauer is an academic researcher from Bristol-Myers Squibb. The author has contributed to research in topics: Gene & Peptide sequence. The author has an hindex of 23, co-authored 42 publications receiving 5407 citations.
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Journal ArticleDOI
The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome
Alejandro Aruffo,Alejandro Aruffo,Mary Farrington,Diane Hollenbaugh,Xu Li,Athena Milatovich,Shigeaki Nonoyama,Jürgen Bajorath,Laura Sue Grosmaire,Ronald E. Stenkamp,Michael G. Neubauer,Robert L. Roberts,Randolph J. Noelle,Jeffrey A. Ledbetter,Uta Francke,Hans D. Ochs +15 more
TL;DR: It is reported that patients with hyper-IgM syndrome (HIM) have a defective gp39-CD40 interaction, which suggests that a defect in gp39 is the basis of X-linked HIM.
Journal ArticleDOI
Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family.
Gregory D. Plowman,Jean-Michel Culouscou,Gena S. Whitney,Janell M. Green,Gary W. Carlton,Linda Foy,Michael G. Neubauer,Mohammed Shoyab +7 more
TL;DR: The findings suggest that this ligand-receptor interaction may play a role in the growth and differentiation of some normal and transformed cells.
Journal ArticleDOI
cDNA cloning and sequence analysis of βig-h3, a novel gene induced in a human adenocarcinoma cell line after treatment with transforming growth factor-β
John E. Skonier,Michael G. Neubauer,Linda Madisen,Kelly L. Bennett,Gregory D. Plowman,A. F. Purchio +5 more
TL;DR: DNA sequence analysis of βig-h3 indicated that it encoded a novel protein, βIG-H3, of 683 amino acids, which contained an amino- terminal secretory sequence and a carboxy-terminal Arg-Gly-Asp (RGD) sequence that can serve as a ligand recognition site for several integrins.
Journal ArticleDOI
Molecular cloning and expression of an additional epidermal growth factor receptor-related gene.
Gregory D. Plowman,Gena S. Whitney,Michael G. Neubauer,Janell M. Green,Vicki L. McDonald,George J. Todaro,Mohammed Shoyab +6 more
TL;DR: The cloning of another member of the human EGF receptor (HER) family of receptor tyrosine kinases, which is named "HER3/ERRB3" is reported and generated peptide-specific antisera that recognizes the 160-kDa HER3 protein when transiently expressed in COS cells.
Journal ArticleDOI
Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand.
Michael A. Bowen,Dhavalkumar D. Patel,X Li,Brett Modrell,Alison R. Malacko,Wei-Chun Wang,Hans Marquardt,Michael G. Neubauer,J M Pesando,U Francke +9 more
TL;DR: In this paper, the authors reported that CD6 expressed by COS cells mediates adhesion to TE cells and that this interaction is specifically blocked with an anti-CD6 monoclonal antibody (mAb) or with a mAb that recognized a TE cell antigen.