M
Michael Malkoch
Researcher at Royal Institute of Technology
Publications - 144
Citations - 6592
Michael Malkoch is an academic researcher from Royal Institute of Technology. The author has contributed to research in topics: Dendrimer & Click chemistry. The author has an hindex of 36, co-authored 137 publications receiving 6017 citations. Previous affiliations of Michael Malkoch include University of California, Santa Barbara & IBM.
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Journal ArticleDOI
Synthesis of well-defined hydrogel networks using Click chemistry
Michael Malkoch,Robert Vestberg,Nalini Gupta,Laetitia Mespouille,Laetitia Mespouille,Philipe Dubois,Andrew F. Mason,James L. Hedrick,Qi Liao,Curtis W. Frank,Kevin Kingsbury,Craig J. Hawker +11 more
TL;DR: New PEG-based hydrogel materials have been synthesized by Click chemistry and shown to result in well-defined networks having significantly improved mechanical properties.
Journal ArticleDOI
Multivalent, bifunctional dendrimers prepared by click chemistry
Peng Wu,Michael Malkoch,Jasmine N. Hunt,Robert Vestberg,Eiton Kaltgrad,M. G. Finn,Valery V. Fokin,K. Barry Sharpless,Craig J. Hawker +8 more
TL;DR: Unsymmetrical dendrimers, containing both mannose binding units and coumarin fluorescent units, have been prepared using click chemistry and shown to be highly efficient, dual-purpose recognition/detection agents for the inhibition of hemagglutination.
Journal ArticleDOI
Structurally diverse dendritic libraries : A highly efficient functionalization approach using Click chemistry
Michael Malkoch,Michael Malkoch,Kristin D. Schleicher,Eric Drockenmuller,Eric Drockenmuller,Craig J. Hawker,Craig J. Hawker,Thomas P. Russell,Peng Wu,Valery V. Fokin +9 more
TL;DR: The high fidelity and efficiency of Click chemistry are exploited in the synthesis of a library of chain end functionalized dendritic macromolecules, demonstrating an evolving synergy between advanced organic chemistry and functional materials.
Journal ArticleDOI
New methodologies in the construction of dendritic materials
TL;DR: This tutorial review describes traditional synthesis of dendritic materials as well as recent advances in synthetic strategies, for example the use of Click chemistry, as a tool to efficiently obtain complex, functional dendrite structures.
Journal ArticleDOI
Orthogonal Approaches to the Simultaneous and Cascade Functionalization of Macromolecules Using Click Chemistry
Michael Malkoch,Raymond J. Thibault,Eric Drockenmuller,Martin Messerschmidt,Brigitte Voit,Thomas P. Russell,Craig J. Hawker +6 more
TL;DR: These single-step strategies for preparing multifunctional macromolecules represent a significant advance as compared to traditional multistep approaches, and the utility of these concepts is demonstrated by selective preparation of a diverse range of orthogonally functionalized vinyl polymers.