Michael P. Lunn

TL;DR: The proportion of cases with unknown cause was higher than that for any specific identified cause, and patients who died were more likely to be immunocompromised than were those who survived (OR = 3·44).

TL;DR: A case series of 43 patients with neurological complications of SARS-CoV-2 infection includes encephalopathies, encephalitis, acute disseminated encephalomyelitis with haemorrhagic change, transverse myelitis, ischaemic stroke, and Guillain-Barré syndrome.

TL;DR: The rate of serious adverse events, serious infections, lymphoma, and congestive heart failure were not statistically significantly different between biologics and control treatment, and direct comparisons revealed that abatacept and anakinra were associated with a significantly lower risk ofserious adverse events compared to most other biologicics.

TL;DR: Duloxetine at 60 mg daily is effective in treating painful diabetic peripheral neuropathy in the short term, with a risk ratio for ≥ 50% pain reduction at 12 weeks of 1.73, and in fibromyalgia, there is low to moderate quality evidence that pain relief is also achieved in pain associated with depressive symptoms, but the NNTB of 8 in Fibromyalgia and depression is not an indication of substantial efficacy.

TL;DR: The first prospective cohort of patients with glycine receptor antibodies are described, with the majority having progressive encephalomyelitis with rigidity and myoclonus and making a good recovery with immunotherapies.