Michal Breker

TL;DR: A fate-mapping study of the murine monocyte and macrophage compartment taking advantage of constitutive and conditional CX(3)CR1 promoter-driven Cre recombinase expression is reported, establishing that short-lived Ly6C(+) monocytes constitute obligatory steady-state precursors of blood-resident Ly 6C(-) cells and that the abundance of Ly6 C(+) blood monocytes dynamically controls the circulation lifespan of their progeny.

TL;DR: In this paper, a fate-mapping study of the macrophage compartment is presented, taking advantage of constitutive and conditional CX(3)CR1 promoter-driven Cre recombinase expression.

TL;DR: Unprecedented proteome plasticity in response to stress in yeast is revealed using a novel screening platform that allows tracking of protein localization and abundance at single-cell resolution.

TL;DR: Methods to study proteomes directly are coming of age, thereby opening new perspectives on the role of post-translational regulation in stabilizing the cellular milieu, and promise that proteomes will soon be studied at a similar level of dynamic resolution as has been the norm for transcriptomes.