Michelle Whirl Carrillo

TL;DR: Dosing recommendations for azathioprine, mercaptopurine (MP), and thioguanine based on TPMT genotype are provided and homozygous wild‐type individuals show lower activeThiopurine nucleolides and less myelosuppression.

TL;DR: Although relevant new evidence has been generated, none of the evidence would change the primary dosing recommendations in the original guideline; therefore, the original publication remains clinically current.

TL;DR: Center for Pharmacogenomics at Washington University, Washington University and St Louis University, St Louis, Missouri, Genome Quebec and Montreal Heart Institute pharmacogenomics Centre, Montreal, Quebec Canada.

TL;DR: This research presents a novel and scalable approach to personalized medicine called “SmartPharm,” which combines cell reprograming, nanofiltration, and “computational medicine” to improve the quality and efficiency of individualized therapy treatment for cancer patients.

TL;DR: These resources illustrate how to integrate pharmacogenomic test results in clinical information systems with CDS to facilitate the use of patient genomic data at the point of care.