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Marc S. Williams
Researcher at Geisinger Health System
Publications - 446
Citations - 20901
Marc S. Williams is an academic researcher from Geisinger Health System. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 67, co-authored 414 publications receiving 18341 citations. Previous affiliations of Marc S. Williams include Primary Children's Hospital & Imperial College London.
Papers
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Journal ArticleDOI
ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing
Robert C. Green,Robert C. Green,Jonathan S. Berg,Wayne W. Grody,Sarah S. Kalia,Bruce R. Korf,Christa Lese Martin,Amy L. McGuire,Robert L. Nussbaum,Julianne M. O’Daniel,Kelly E. Ormond,Heidi L. Rehm,Heidi L. Rehm,Michael S. Watson,Marc S. Williams,Leslie G. Biesecker +15 more
TL;DR: It is recommended that laboratories performing clinical sequencing seek and report mutations of the specified classes or types in the genes listed here and encourage the creation of an ongoing process for updating these recommendations at least annually as further data are collected.
Journal ArticleDOI
The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future
Omri Gottesman,Helena Kuivaniemi,Gerard Tromp,W. Andrew Faucett,Rongling Li,Teri A. Manolio,Saskia C. Sanderson,Joseph L. Kannry,Randi E. Zinberg,Melissa A. Basford,Murray H. Brilliant,David J. Carey,Rex L. Chisholm,Christopher G. Chute,John Connolly,David R. Crosslin,Joshua C. Denny,Carlos J. Gallego,Jonathan L. Haines,Hakon Hakonarson,John B. Harley,Gail P. Jarvik,Isaac S. Kohane,Iftikhar J. Kullo,Eric B. Larson,Catherine A. McCarty,Marylyn D. Ritchie,Dan M. Roden,Maureen E. Smith,Erwin P. Bottinger,Marc S. Williams +30 more
TL;DR: The evolution, accomplishments, opportunities, and challenges of the network are described, from its inception as a five- group consortium focused on genotype–phenotype associations for genomic discovery to its current form as a nine-group consortium pivoting toward the implementation of genomic medicine.
Book
Contesting global governance : multilateral economic institutions and global social movements
TL;DR: In this article, the authors investigate complex multilateralism by studying the relationship between three multilateral economic institutions (the IMF, World Bank, and World Trade Organization) and three global social movements (environmental, labour and women's movements).
Journal ArticleDOI
Implementing genomic medicine in the clinic: the future is here
Teri A. Manolio,Rex L. Chisholm,Brad Ozenberger,Dan M. Roden,Marc S. Williams,Richard Trevor Wilson,David P. Bick,Erwin P. Bottinger,Murray H. Brilliant,Charis Eng,Kelly A. Frazer,Bruce R. Korf,David H. Ledbetter,James R. Lupski,Clay B. Marsh,David A. Mrazek,Michael F. Murray,Peter H. O'Donnell,Daniel J. Rader,Mary V. Relling,Alan R. Shuldiner,David Valle,Richard M. Weinshilboum,Eric D. Green,Geoffrey S. Ginsburg +24 more
TL;DR: The National Human Genome Research Institute brought together a number of institutions to describe their ongoing projects and challenges, identify common infrastructure and research needs, and outline an implementation framework for investigating and introducing similar programs elsewhere.
Journal ArticleDOI
An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.
Catherine A. Brownstein,Alan H. Beggs,Nils Homer,Barry Merriman,Timothy W. Yu,Katherine C. Flannery,Elizabeth T. DeChene,Meghan C. Towne,Sarah K. Savage,Emily N. Price,Ingrid A. Holm,Lovelace J. Luquette,Elaine Lyon,Joseph A. Majzoub,Peter Neupert,David McCallie,Peter Szolovits,Huntington F. Willard,Nancy J. Mendelsohn,Renee Temme,Richard S. Finkel,Sabrina W. Yum,Livija Medne,Shamil R. Sunyaev,Ivan Adzhubey,Christopher A. Cassa,Paul I.W. de Bakker,Paul I.W. de Bakker,Hatice Duzkale,Piotr Dworzynski,William G. Fairbrother,Laurent C. Francioli,Birgit Funke,Monica A. Giovanni,Robert E. Handsaker,Kasper Lage,Matthew S. Lebo,Monkol Lek,Ignaty Leshchiner,Daniel G. MacArthur,Heather M. McLaughlin,Michael F. Murray,Tune H. Pers,Paz Polak,Soumya Raychaudhuri,Heidi L. Rehm,Rachel Soemedi,Nathan O. Stitziel,Sara Vestecka,Jochen Supper,Claudia Gugenmus,Bernward Klocke,Alexander Hahn,Max Schubach,Mortiz Menzel,Saskia Biskup,Peter Freisinger,Mario Deng,Martin Braun,Sven Perner,Richard J.H. Smith,Janeen L. Andorf,Jian Huang,Kelli K. Ryckman,Val C. Sheffield,Val C. Sheffield,Edwin M. Stone,Edwin M. Stone,Thomas B. Bair,E. Ann Black-Ziegelbein,Terry A. Braun,Benjamin W. Darbro,Adam P. DeLuca,Diana L. Kolbe,Todd E. Scheetz,Aiden Eliot Shearer,Rama Sompallae,Kai Wang,Alexander G. Bassuk,Erik Edens,Katherine D. Mathews,Steven A. Moore,Oleg A. Shchelochkov,Pamela Trapane,Aaron D. Bossler,Colleen A. Campbell,Jonathan W. Heusel,Anne E. Kwitek,Tara Maga,Karin Panzer,Thomas H. Wassink,Douglas J. Van Daele,Hela Azaiez,Kevin T. Booth,Nic Meyer,Michael M. Segal,Marc S. Williams,Gerard Tromp,Peter White,Donald J. Corsmeier,Sara Fitzgerald-Butt,Gail E. Herman,Devon Lamb-Thrush,Kim L. McBride,David L. Newsom,Christopher R. Pierson,Alexander T. Rakowsky,Aleš Maver,Luca Lovrečić,Anja Palandačić,Anja Palandačić,Borut Peterlin,Ali Torkamani,Anna Wedell,Anna Wedell,Anna Wedell,Mikael Huss,Andrey Alexeyenko,Jessica M. Lindvall,Måns Magnusson,Måns Magnusson,Måns Magnusson,Daniel Nilsson,Daniel Nilsson,Daniel Nilsson,Henrik Stranneheim,Henrik Stranneheim,Henrik Stranneheim,Fulya Taylan,Christian Gilissen,Alexander Hoischen,Bregje W.M. van Bon,Helger G. Yntema,Marcel R. Nelen,Weidong Zhang,Jason Sager,Lu Zhang,Kathryn Blair,Deniz Kural,Michael Cariaso,Greg Lennon,Asif Javed,Saloni Agrawal,Pauline C. Ng,Komal S. Sandhu,Shuba Krishna,Vamsi Veeramachaneni,Ofer Isakov,Eran Halperin,Eitan Friedman,Noam Shomron,Gustavo Glusman,Jared C. Roach,Juan Caballero,Hannah C. Cox,Denise E. Mauldin,Seth A. Ament,Lee Rowen,Daniel R. Richards,F. Anthony San Lucas,Manuel L. Gonzalez-Garay,C. Thomas Caskey,Yu Bai,Ying Huang,Fang Fang,Yan Zhang,Zhengyuan Wang,Jorge Barrera,Juan M. García-Lobo,Domingo González-Lamuño,Javier Llorca,María Cruz Rodríguez,Ignacio Varela,Martin G. Reese,Francisco M. De La Vega,Edward S. Kiruluta,Michele Cargill,Reece K. Hart,Jon M. Sorenson,Gholson J. Lyon,Gholson J. Lyon,David A. Stevenson,Bruce E. Bray,Barry Moore,Karen Eilbeck,Mark Yandell,Hongyu Zhao,Lin Hou,Xiaowei Chen,Xiting Yan,Mengjie Chen,Cong Li,Can Yang,Murat Gunel,Peining Li,Yong Kong,Austin C. Alexander,Zayed Albertyn,Kym M. Boycott,Dennis E. Bulman,Paul M. K. Gordon,A. Micheil Innes,Bartha Maria Knoppers,Jacek Majewski,Christian R. Marshall,Jillian S. Parboosingh,Sarah L. Sawyer,Mark E. Samuels,Jeremy Schwartzentruber,Isaac S. Kohane,David M. Margulies +210 more
TL;DR: The CLARITY Challenge provides a comprehensive assessment of current practices for using genome sequencing to diagnose and report genetic diseases and reveals a general convergence of practices on most elements of the analysis and interpretation process.