J
J K Hicks
Researcher at St. Jude Children's Research Hospital
Publications - 8
Citations - 1658
J K Hicks is an academic researcher from St. Jude Children's Research Hospital. The author has contributed to research in topics: PharmGKB & Desipramine. The author has an hindex of 8, co-authored 8 publications receiving 1460 citations.
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Journal ArticleDOI
Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update
J K Hicks,Katrin Sangkuhl,Jesse J. Swen,Vicki L. Ellingrod,Daniel J. Müller,K Shimoda,Jeffrey R. Bishop,Evan D. Kharasch,Todd C. Skaar,Andrea Gaedigk,Henry M. Dunnenberger,Teri E. Klein,Kelly E. Caudle,Julia C. Stingl +13 more
TL;DR: In this paper, an update to the 2012 Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2D6 and CYP 2C19 Genotypes and Dosing of Tricyclic Antidepressants is presented.
Journal ArticleDOI
Clinical Pharmacogenetics Implementation Consortium guideline for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants
J K Hicks,Jesse J. Swen,Caroline F. Thorn,Katrin Sangkuhl,Evan D. Kharasch,Vicki L. Ellingrod,Todd C. Skaar,Daniel J. Müller,Andrea Gaedigk,Julia C. Stingl +9 more
TL;DR: In this paper, the efficacy and safety of tricyclic antidepressants were evaluated using genotype-directed dosing of CYP2D6 and C19 polymorphic enzymes.
Journal ArticleDOI
Clinical Pharmacogenetics Implementation Consortium Guidelines for Thiopurine Methyltransferase Genotype and Thiopurine Dosing: 2013 Update
Mary V. Relling,Eric E. Gardner,William J. Sandborn,Kjeld Schmiegelow,C H Pui,Sook Wah Yee,Charles M. Stein,Michelle Whirl Carrillo,William E. Evans,J K Hicks,Matthias Schwab,Matthias Schwab,Teri E. Klein +12 more
TL;DR: Although relevant new evidence has been generated, none of the evidence would change the primary dosing recommendations in the original guideline; therefore, the original publication remains clinically current.
Journal ArticleDOI
Pharmacogenomics and individualized medicine: translating science into practice.
TL;DR: Key components to successful clinical implementation of pharmacogenomics will include consistent interpretation of Pharmacogenomics test results, availability of clinical guidelines for prescribing on the basis of testresults, and knowledge‐based decision support systems.
The Pharmacogenomics Research Network Translational Pharmacogenetics Program: Overcoming Challenges of Real-World
TL;DR: The Clinical Pharmacogenetics Implementation Consortium (CPIC) as mentioned in this paper is a shared initiative between the Pharmacogenomics Knowledgebase (PharmGKB) and the PGRN, which aims to identify barriers and develop real-world solutions to implementation of evidence-based pharmacogenetic tests.