M
Michio Murata
Researcher at Osaka University
Publications - 299
Citations - 11594
Michio Murata is an academic researcher from Osaka University. The author has contributed to research in topics: Maitotoxin & Lipid bilayer. The author has an hindex of 50, co-authored 288 publications receiving 10668 citations. Previous affiliations of Michio Murata include Kitasato University & Tohoku University.
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Journal ArticleDOI
Sphingomyelins and ent-Sphingomyelins Form Homophilic Nano-Subdomains within Liquid Ordered Domains
Yo Yano,Shinya Hanashima,Hiroshi Tsuchikawa,Tomokazu Yasuda,J. Peter Slotte,Erwin London,Michio Murata +6 more
TL;DR: Results suggest that (even in the absence of ent-SM) SM-SM interactions play a crucial role in forming nano-subdomains within liquid-ordered domains and may be a key feature of lipid microdomains in biological membranes.
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Amphotericin B covalent dimers with carbonyl-amino linkage: a new probe for investigating ion channel assemblies
TL;DR: Dimmer 4 with a longer linker revealed K+ ion flux activity, suggesting that some distance and/or flexibility between the carboxyl and amino groups in adjacent molecules is required for the formation of ion-permeable complex in biomembranes.
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Mosquito larvicidal limonoids from the fruits of Chisocheton erythrocarpus Hiern
Soon-Lim Chong,Arshia Hematpoor,Hazrina Hazni,Mohd Sofian-Azirun,Marc Litaudon,Unang Supratman,Michio Murata,Khalijah Awang +7 more
TL;DR: Mosquito larvicidal activity of the limonoids revealed that 4 and 5 were toxic to larvae of Aedes aegypti, Aedes albopictus and Culex Quinquefasciatus.
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Highly efficient preparation of selectively isotope cluster-labeled long chain fatty acids via two consecutive C(sp3)-C(sp3) cross-coupling reactions.
TL;DR: An efficient synthesis involving two copper-catalyzed alkyl-alkyl coupling reactions has been designed to easily access doubly isotope-labeled fatty acids and will be further used for determining the conformation of anAlkyl chain of lipidic biomolecules upon interaction with proteins.
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Pivotal Role of Interdigitation in Interleaflet Interactions: Implications from Molecular Dynamics Simulations.
TL;DR: The phase behavior of asymmetric membranes is investigated using coarse-grained molecular dynamics simulations and it is determined that interdigitated acyl chains modulated the partitioning of Chol in the opposing leaflet, resulting in phase separation.