M
Mignon L. Loh
Researcher at University of California, San Francisco
Publications - 472
Citations - 42124
Mignon L. Loh is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Leukemia & Medicine. The author has an hindex of 82, co-authored 407 publications receiving 35918 citations. Previous affiliations of Mignon L. Loh include Children's Oncology Group & Brigham and Women's Hospital.
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Journal ArticleDOI
Excellent Outcomes With Reduced Frequency of Vincristine and Dexamethasone Pulses in Standard-Risk B-Lymphoblastic Leukemia: Results From Children's Oncology Group AALL0932.
Anne L. Angiolillo,Anne L. Angiolillo,Reuven J. Schore,Reuven J. Schore,John A. Kairalla,Meenakshi Devidas,Karen R. Rabin,Patrick A. Zweidler-McKay,Michael J. Borowitz,Brent L. Wood,Andrew J. Carroll,Nyla A. Heerema,Mary V. Relling,Johann K. Hitzler,Ashley R. Lane,Kelly W. Maloney,Cindy Wang,Mylene Bassal,William L. Carroll,Naomi J. Winick,Elizabeth A. Raetz,Mignon L. Loh,Stephen P. Hunger +22 more
TL;DR: AALL0932 as mentioned in this paper evaluated two randomized maintenance interventions to optimize disease-free survival (DFS) while reducing the burden of therapy in children with newly diagnosed NCI standard-risk.
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Comparison of high-dose methotrexate (HD-MTX) with Capizzi methotrexate plus asparaginase (C-MTX/ASNase) in children and young adults with high-risk acute lymphoblastic leukemia (HR-ALL): A report from the Children’s Oncology Group Study AALL0232.
Eric Larsen,Wanda L. Salzer,Meenakshi Devidas,James B. Nachman,Elizabeth A. Raetz,Mignon L. Loh,Nyla A. Heerema,Andrew J. Carroll,Julie M. Gastier-Foster,Michael J. Borowitz,Brent L. Wood,C. L. Willman,Naomi Winick,Stephen P. Hunger,William L. Carroll +14 more
TL;DR: 3 The full, final text of this abstract will be available in Part II of the 2011 Annual Meeting Proceedings, distributed onsite at the Meeting on June 4,2011, and as a supplement to the June 20, 2011, issue of Journal of Clinical Oncology.
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Advancing RAS/RASopathy therapies: An NCI-sponsored intramural and extramural collaboration for the study of RASopathies.
Andrea M. Gross,Megan N. Frone,Karen W. Gripp,Bruce D. Gelb,Lisa Schoyer,Lisa Schill,Beth Stronach,Leslie G. Biesecker,Dominic Esposito,Edjay R. Hernandez,Eric Legius,Mignon L. Loh,Staci Martin,Deborah K. Morrison,Katherine A. Rauen,Pamela L. Wolters,Dina Zand,Frank McCormick,Sharon A. Savage,Douglas R. Stewart,Brigitte C. Widemann,Marielle E. Yohe +21 more
TL;DR: The Advancing RAS/RASopathy Therapies (ART) initiative as mentioned in this paper was developed to develop effective therapies and prevention strategies for the clinical manifestations of the non-NF1 RASopathies and for tumors characterized by somatic RAS mutations.
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Small Molecule Inhibitor that Stabilizes the Autoinhibited Conformation of the Oncogenic Tyrosine Phosphatase SHP2
Xiaoqin Wu,Gang Xu,Xiaobo Li,Xiaobo Li,Weiren Xu,Qianjin Li,Wei Liu,Karen A. Kirby,Mignon L. Loh,Jun Li,Stefan G. Sarafianos,Cheng-Kui Qu,Cheng-Kui Qu +12 more
TL;DR: This small molecule SHP2 inhibitor has a potential to serve as a lead compound for further optimization studies to develop novel anti-SHP2 therapeutic agents.
Journal ArticleDOI
Novel susceptibility variants at the ERG locus for childhood acute lymphoblastic leukemia in Hispanics.
Maoxiang Qian,Maoxiang Qian,Maoxiang Qian,Heng Xu,Virginia Perez-Andreu,Virginia Perez-Andreu,Kathryn G. Roberts,Hui Zhang,Wenjian Yang,Shouyue Zhang,Xujie Zhao,Colton Smith,Meenakshi Devidas,Julie M. Gastier-Foster,Julie M. Gastier-Foster,Elizabeth A. Raetz,Eric Larsen,Esteban G. Burchard,Naomi J. Winick,W. Paul Bowman,Paul L. Martin,Michael J. Borowitz,Brent L. Wood,Federico Antillon-Klussmann,Ching-Hon Pui,Charles G. Mullighan,William E. Evans,Stephen P. Hunger,Stephen P. Hunger,Mary V. Relling,Mignon L. Loh,Mignon L. Loh,Jun J. Yang +32 more
TL;DR: A novel susceptibility locus in the ERG gene is identified and its contribution to racial disparity in this cancer is contributed to by increasing Native American genetic ancestry.