D
Deborah K. Morrison
Researcher at National Institutes of Health
Publications - 105
Citations - 11939
Deborah K. Morrison is an academic researcher from National Institutes of Health. The author has contributed to research in topics: MAPK/ERK pathway & Kinase. The author has an hindex of 47, co-authored 96 publications receiving 10913 citations. Previous affiliations of Deborah K. Morrison include Science Applications International Corporation.
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Journal ArticleDOI
Comparative Genomics of the Eukaryotes
Gerald M. Rubin,Mark Yandell,Jennifer R. Wortman,George L. Gabor,Miklos,Catherine R. Nelson,Iswar K. Hariharan,Mark E. Fortini,Peter W. Li,Rolf Apweiler,Wolfgang Fleischmann,J. Michael Cherry,Steven Henikoff,Marian P. Skupski,Sima Misra,Michael Ashburner,Ewan Birney,Mark S. Boguski,Thomas Brody,Peter Brokstein,Susan E. Celniker,Stephen A. Chervitz,David Coates,Anibal Cravchik,Andrei Gabrielian,Richard F. Galle,William M. Gelbart,Reed A. George,Lawrence S.B. Goldstein,Fangcheng Gong,Ping Guan,Nomi L. Harris,Bruce A. Hay,Roger A. Hoskins,Jiayin Li,Zhenya Li,Richard O. Hynes,Steven J.M. Jones,Peter M. Kuehl,Bruno Lemaitre,J. Troy Littleton,Deborah K. Morrison,Christopher J. Mungall,Patrick H. O'Farrell,Oxana K. Pickeral,Chris Shue,Leslie B. Vosshall,Jiong Zhang,Qi Zhao,Xiangqun H. Zheng,Fei Zhong,Wenyan Zhong,Richard A. Gibbs,J. Craig Venter,Mark Raymond Adams,Suzanna E. Lewis +55 more
TL;DR: The fly has orthologs to 177 of the 289 human disease genes examined and provides the foundation for rapid analysis of some of the basic processes involved in human disease.
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Regulation of MAP kinase signaling modules by scaffold proteins in mammals.
TL;DR: The evidence that supports a physiologically relevant role of MAPK scaffold proteins in mammals is critically evaluated.
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MAP Kinase Pathways
TL;DR: MAP kinases are activated within protein kinase cascades that regulate cell proliferation, differentiation, and death and are grouped into three families: ERKs, JNKs, and p38/SAPKs.
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Regulation of Raf-1 by Direct Feedback Phosphorylation
Michele K. Dougherty,Jürgen Müller,Daniel A. Ritt,Ming Zhou,Xiao Zhen Zhou,Terry D. Copeland,Thomas P. Conrads,Timothy D. Veenstra,Kun Ping Lu,Deborah K. Morrison +9 more
TL;DR: Six phosphorylation sites are identified that contribute to the downregulation of Raf-1 after mitogen stimulation and elucidate a critical Raf- 1 regulatory mechanism that contributes to the sensitive, temporal modulation of Ras signaling.
Journal ArticleDOI
The 14-3-3 proteins: integrators of diverse signaling cues that impact cell fate and cancer development
TL;DR: This review examines the recent advances that further elucidate the role of 14-3-3 proteins as integrators of diverse signaling cues that influence cell fate decisions and tumorigenesis.