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Mika Skeppholm

Researcher at Karolinska Institutet

Publications -  21
Citations -  1015

Mika Skeppholm is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Dabigatran & Thromboelastometry. The author has an hindex of 15, co-authored 20 publications receiving 896 citations. Previous affiliations of Mika Skeppholm include Karolinska University Hospital.

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The Changing Landscape for Stroke Prevention in AF: Findings From the GLORIA-AF Registry Phase 2

Menno V. Huisman, +1027 more
TL;DR: GLORIA-AF (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation) is a prospective, global registry program describing antithrombinotic t...
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Benefit of Anticoagulation Unlikely in Patients With Atrial Fibrillation and a CHA2DS2-VASc Score of 1

TL;DR: The risk of ischemic stroke in patients with atrial fibrillation and a CHA2DS2-VASc score of 1 seems to be lower than previously reported.
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Evaluation of coagulation assays versus LC-MS/MS for determinations of dabigatran concentrations in plasma

TL;DR: LC-MS/MS is the gold standard for measurements of dabigatran in plasma, and either HTI or ECA assays may be used, but neither of these assays is dependable when monitoring low levels or to infer total absence of dabIGatran.
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Platelet-derived microparticles during and after acute coronary syndrome

TL;DR: PMP concentrations follow the pattern of platelet activation during and after an ACS, and decreased concentrations are observed after initiation of antithrombotic treatment, but PMP exposing CD62P or CD142 are still elevated after six months.
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Clinical evaluation of laboratory methods to monitor apixaban treatment in patients with atrial fibrillation.

TL;DR: Anti-FXa-assay performed well upon apixaban concentrations in a normal exposure range, and still LC-MS/MS remains the "gold standard" method, covering also low concentrations.