M
Min Han
Researcher at University of Colorado Boulder
Publications - 189
Citations - 15761
Min Han is an academic researcher from University of Colorado Boulder. The author has contributed to research in topics: Caenorhabditis elegans & Gene. The author has an hindex of 67, co-authored 174 publications receiving 14875 citations. Previous affiliations of Min Han include Fudan University & University of California, Los Angeles.
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Journal ArticleDOI
Efficient Transposition of the piggyBac (PB) Transposon in Mammalian Cells and Mice
TL;DR: It is shown that piggyBac elements carrying multiple genes can efficiently transpose in human and mouse cell lines and also in mice, providing a first and critical step toward a highly efficient transposon system for a variety of genetic manipulations in mice and other vertebrates.
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Nucleosome loss activates yeast downstream promoters in vivo
Min Han,Michael Grunstein +1 more
TL;DR: It is suggested that nucleosome loss increases transcription initiation and subsequent elongation in vivo and also indicates that the proteins which recognize the downstream promoter are activated and functional, at least in part, even in the absence of the UAS complex.
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A 5-bp deletion in ELOVL4 is associated with two related forms of autosomal dominant macular dystrophy
Kang Zhang,Kang Zhang,Marina Kniazeva,Min Han,Wen Li,Zhengya Yu,Zhenglin Yang,Yang Li,Michael L. Metzker,Rando Allikmets,Donald J. Zack,Laura E. Kakuk,Pamela S. Lagali,Paul Wong,Ian M. MacDonald,Paul A. Sieving,David J. Figueroa,Christopher P. Austin,Robert J. Gould,Radha Ayyagari,Konstantin Petrukhin +20 more
TL;DR: These results are the first to implicate the biosynthesis of fatty acids in the pathogenesis of inherited macular degeneration and identify a single 5-bp deletion within the protein-coding region of a new retinal photoreceptor-specific gene, ELOVL4, in all affected members of STGD3 and adMD families.
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Extremely conserved histone H4 N terminus is dispensable for growth but essential for repressing the silent mating loci in yeast
TL;DR: Surprisingly, removal of the H4 N terminus also derepresses the silent mating type loci, HML alpha and HMRa, disrupting mating, and this activation is specific since other regulated genes are repressed and induced normally in these cells.
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SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.
Xiaochang Zhang,Kai Lei,Xiao-bing Yuan,Xiaohui Wu,Yuan Zhuang,Yuan Zhuang,Tian Xu,Tian Xu,Rener Xu,Min Han,Min Han +10 more
TL;DR: It is shown that SUN1 and SUN2 redundantly form complexes with Syne-2 to mediate the centrosome-nucleus coupling during both INM and radial neuronal migration in the cerebral cortex, filling an important gap in the understanding of the mechanism of nuclear movement during brain development.