M
Min Mao
Researcher at Shanghai Jiao Tong University
Publications - 12
Citations - 212
Min Mao is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Osteosarcoma & STAT3. The author has an hindex of 6, co-authored 10 publications receiving 120 citations.
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Journal ArticleDOI
Anlotinib, a novel small molecular tyrosine kinase inhibitor, suppresses growth and metastasis via dual blockade of VEGFR2 and MET in osteosarcoma
Gangyang Wang,Mengxiong Sun,Yafei Jiang,Tao Zhang,Wei Sun,Hongsheng Wang,Fei Yin,Zhuoying Wang,Weilin Sang,Jing Xu,Min Mao,Dongqing Zuo,Zifei Zhou,Chongren Wang,Zeze Fu,Zongyi Wang,Zhenfeng Duan,Yingqi Hua,Zhengdong Cai +18 more
TL;DR: Preclinical work indicates that anlotinib acts as a novel inhibitor of VEGFR2 and MET that blocks tumorigenesis in osteosarcoma, which could be translated into future clinical trials.
Journal ArticleDOI
Inhibition of CaMKIIα Activity Enhances Antitumor Effect of Fullerene C60 Nanocrystals by Suppression of Autophagic Degradation.
Jing Xu,Hongsheng Wang,Yi Hu,Yu Shrike Zhang,Longping Wen,Fei Yin,Zhuoying Wang,Yingchao Zhang,Suoyuan Li,Yanyan Miao,Binhui Lin,Dongqing Zuo,Gangyang Wang,Min Mao,Tao Zhang,Jianxun Ding,Yingqi Hua,Zhengdong Cai +17 more
TL;DR: Nano‐C60 is demonstrated to elicit reactive oxygen species (ROS)‐dependent cytotoxicity and persistent activation of CaMKIIα in osteosarcoma (OS) cells and presents a promising strategy for improving the antitumor efficacy of nano‐C 60.
Journal ArticleDOI
Attenuation of STAT3 Phosphorylation Promotes Apoptosis and Chemosensitivity in Human Osteosarcoma Induced by Raddeanin A.
Zhuoying Wang,Chongren Wang,Dongqing Zuo,Zhang Tao,Fei Yin,Zifei Zhou,Hongsheng Wang,Jing Xu,Min Mao,Gangyang Wang,Yingqi Hua,Wei Sun,Zhengdong Cai +12 more
TL;DR: RA suppressed in vivo tumor growth and induced apoptosis in nude mouse using drug-resistant OS tibia orthotopic model and is a promising potential therapeutic for the treatment of doxorubicin resistance in OS.
Journal ArticleDOI
Glaucocalyxin A-induced oxidative stress inhibits the activation of STAT3 signaling pathway and suppresses osteosarcoma progression in vitro and in vivo.
Min Mao,Tao Zhang,Zhuoying Wang,Hongsheng Wang,Jing Xu,Fei Yin,Gangyang Wang,Mengxiong Sun,Zongyi Wang,Yingqi Hua,Zhengdong Cai +10 more
TL;DR: It is demonstrated that GLA could exhibit potent anticancer effects through effectively blocking the STAT3 signaling pathway, which was induced by ROS-mediated oxidative stress in OS in vitro and in vivo.
Journal ArticleDOI
Antitumor activity of Raddeanin A is mediated by Jun amino-terminal kinase activation and signal transducer and activator of transcription 3 inhibition in human osteosarcoma.
Zhuoying Wang,Jiakang Shen,Jiakang Shen,Wei Sun,Tao Zhang,Dongqing Zuo,Hongsheng Wang,Gangyang Wang,Jing Xu,Fei Yin,Min Mao,Zifei Zhou,Yingqi Hua,Zhengdong Cai +13 more
TL;DR: Results show that RA suppresses proliferation and induces apoptosis by modulating the JNK/c‐Jun and STAT3 signaling pathways in human osteosarcoma, and may be a promising candidate antitumor drug for osteosARcoma intervention.