S
Satoshi Inoue
Researcher at Saitama Medical University
Publications - 482
Citations - 23022
Satoshi Inoue is an academic researcher from Saitama Medical University. The author has contributed to research in topics: Estrogen receptor & Prostate cancer. The author has an hindex of 69, co-authored 450 publications receiving 20746 citations. Previous affiliations of Satoshi Inoue include Nihon University & Johns Hopkins University School of Medicine.
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TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity
Michaela U. Gack,Young C. Shin,Chul Hyun Joo,Chul Hyun Joo,Tomohiko Urano,Tomohiko Urano,Chengyu Liang,Lijun Sun,Osamu Takeuchi,Shizuo Akira,Zhijian J. Chen,Satoshi Inoue,Satoshi Inoue,Jae U. Jung +13 more
TL;DR: It is demonstrated that TRIM25 E3 ubiquitin ligase induces the Lys 63-linked ubiquitination of RIG-I, which is crucial for the cytosolic Rig-I signalling pathway to elicit host antiviral innate immunity.
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Influenza A Virus NS1 Targets the Ubiquitin Ligase TRIM25 to Evade Recognition by the Host Viral RNA Sensor RIG-I
Michaela U. Gack,Randy A. Albrecht,Tomohiko Urano,Tomohiko Urano,Kyung-Soo Inn,Kyung-Soo Inn,I-Chueh Huang,Elena Carnero,Michael Farzan,Satoshi Inoue,Satoshi Inoue,Jae U. Jung,Jae U. Jung,Adolfo García-Sastre +13 more
TL;DR: This work reports that the influenza A virus nonstructural protein 1 (NS1) specifically inhibits TRIM25-mediated RIG-I CARD ubiquitination, thereby suppressing Rig-I signal transduction and revealing a mechanism by which influenza virus inhibits host IFN response.
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Interaction of Phytoestrogens with Estrogen Receptors α and β
Keiko Morito,Toshiharu Hirose,Junei Kinjo,Tomoki Hirakawa,Masafumi Okawa,Toshihiro Nohara,Sumito Ogawa,Satoshi Inoue,Masami Muramatsu,Yukito Masamune +9 more
TL;DR: The estrogenic activities of soy isoflavones after digestion with enteric bacteria in competition binding assays with hER alpha or hER beta protein, and in a gene expression assay using a yeast system were investigated by the growth of MCF-7 breast cancer cells.
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Association of bone mineral density with polymorphism of the estrogen receptor gene
TL;DR: It is suggested that some variation of the ER gene linked to these RFLPs is associated with low BMD and that this at least partly explains the cause of postmenopausal osteoporosis in Japanese women.
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The complete primary structure of human estrogen receptor beta (hER beta) and its heterodimerization with ER alpha in vivo and in vitro.
Sumito Ogawa,Satoshi Inoue,Satoshi Inoue,Toru Watanabe,Hisahiko Hiroi,Akira Orimo,Takayuki Hosoi,Yasuyoshi Ouchi,Masami Muramatsu +8 more
TL;DR: This study indicates that ER alpha and ER beta can interact in vivo, cross-signaling each other.