H
Haining Yang
Researcher at University of Hawaii
Publications - 98
Citations - 7826
Haining Yang is an academic researcher from University of Hawaii. The author has contributed to research in topics: Mesothelioma & Cancer. The author has an hindex of 38, co-authored 91 publications receiving 6350 citations. Previous affiliations of Haining Yang include Loyola University Chicago & University of Hawaii at Manoa.
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Journal ArticleDOI
Germline BAP1 mutations predispose to malignant mesothelioma
Joseph R. Testa,Mitchell Cheung,Jianming Pei,Jennifer E. Below,Yinfei Tan,Eleonora Sementino,Nancy J. Cox,A. Umran Dogan,A. Umran Dogan,Harvey I. Pass,Sandra Trusa,Mary Hesdorffer,Masaki Nasu,Amy Powers,Zeyana Rivera,Sabahattin Cömertpay,Mika Tanji,Giovanni Gaudino,Haining Yang,Michele Carbone +19 more
TL;DR: A BAP1-related cancer syndrome is identified that is characterized by mesothelioma and uveal melanoma, and it is hypothesized that other cancers may also be involved and that mesot helioma predominates upon asbestos exposure.
Journal ArticleDOI
Consensus guidelines for the detection of immunogenic cell death
Oliver Kepp,Laura Senovilla,Ilio Vitale,Erika Vacchelli,Sandy Adjemian,Patrizia Agostinis,Lionel Apetoh,Fernando Aranda,Vincenzo Barnaba,Norma Bloy,Laura Bracci,Karine Breckpot,David Brough,Aitziber Buqué,Maria G. Castro,Mara Cirone,María Isabel Colombo,Isabelle Cremer,Sandra Demaria,Luciana Dini,Aristides G. Eliopoulos,Alberto Faggioni,Silvia C. Formenti,Jitka Fucikova,Lucia Gabriele,Udo S. Gaipl,Jérôme Galon,Abhishek D. Garg,François Ghiringhelli,Nathalia A. Giese,Zong Sheng Guo,Akseli Hemminki,Martin Herrmann,James W. Hodge,Stefan Holdenrieder,Jamie Honeychurch,Hong-Min Hu,Xing Huang,Timothy M Illidge,Koji Kono,Mladen Korbelik,Dmitri V. Krysko,Sherene Loi,Pedro R. Lowenstein,Enrico Lugli,Yuting Ma,Frank Madeo,Angelo A. Manfredi,Isabelle Martins,Domenico Mavilio,Laurie Menger,Nicolò Merendino,Michael Michaud,Grégoire Mignot,Karen L. Mossman,Gabriele Multhoff,Rudolf Oehler,Fabio Palombo,Theocharis Panaretakis,Jonathan Pol,Enrico Proietti,Jean-Ehrland Ricci,Chiara Riganti,Patrizia Rovere-Querini,Anna Rubartelli,Antonella Sistigu,Mark J. Smyth,Juergen Sonnemann,Radek Spisek,John Stagg,Abdul Qader Sukkurwala,Eric Tartour,Andrew Thorburn,Stephen H. Thorne,Peter Vandenabeele,Francesca Velotti,Samuel T Workenhe,Haining Yang,Wei-Xing Zong,Laurence Zitvogel,Guido Kroemer,Lorenzo Galluzzi +81 more
TL;DR: Strategies conceived to detect surrogate markers of ICD in vitro and to screen large chemical libraries for putative I CD inducers are outlined, based on a high-content, high-throughput platform that was recently developed.
Journal ArticleDOI
BAP1 and cancer
TL;DR: Findings indicate that germline BAP1 mutations cause a novel cancer syndrome that is characterized by the onset at an early age of benign melanocytic skin tumours with mutated B AP1, and later in life by a high incidence of mesothelioma, uveal melanoma, cutaneous melanoma and possibly additional cancers.
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Malignant Mesothelioma: Facts, Myths and Hypotheses
Michele Carbone,Bevan H. Ly,Ronald F. Dodson,Ian Pagano,Paul Morris,Paul Morris,Umran A. Dogan,Umran A. Dogan,Adi F. Gazdar,Harvey I. Pass,Haining Yang,Haining Yang +11 more
TL;DR: It is estimated that about 50–80% of pleural MM in men and 20–30% in women developed in individuals whose history indicates asbestos exposure(s) above that expected from most background settings, and about 30% of peritoneal mesothelioma in men has been associated with exposure to asbestos.
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BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation
Angela Bononi,Carlotta Giorgi,Simone Patergnani,David Larson,Kaitlyn Verbruggen,Mika Tanji,Laura Pellegrini,Valentina Signorato,Valentina Signorato,Federica Olivetto,Federica Olivetto,Sandra Pastorino,Masaki Nasu,Andrea Napolitano,Giovanni Gaudino,Paul Morris,Greg Sakamoto,Laura K. Ferris,Alberto Danese,Andrea Raimondi,Carlo Tacchetti,Shafi Kuchay,Harvey I. Pass,El Bachir Affar,Haining Yang,Paolo Pinton,Michele Carbone +26 more
TL;DR: This work discovers that BAP1 localizes at the endoplasmic reticulum, and binds, deubiquitylates, and stabilizes type 3 inositol-1,4,5-trisphosphate receptor (IP3R3), modulating calcium release into the cytosol and mitochondria, promoting apoptosis.