M
Mohammad Rashedul Islam
Researcher at Harvard University
Publications - 15
Citations - 228
Mohammad Rashedul Islam is an academic researcher from Harvard University. The author has contributed to research in topics: Medicine & Neuroprotection. The author has an hindex of 6, co-authored 11 publications receiving 81 citations. Previous affiliations of Mohammad Rashedul Islam include University of Pittsburgh & Texas Tech University Health Sciences Center.
Papers
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Journal ArticleDOI
Exercise hormone irisin is a critical regulator of cognitive function.
Mohammad Rashedul Islam,Sophia Valaris,Michael F. Young,Erin B. Haley,Renhao Luo,Sabrina F. Bond,Sabrina F. Bond,Sofia Mazuera,Sofia Mazuera,Robert R. Kitchen,Barbara J. Caldarone,Luis E.B. Bettio,Brian R. Christie,Angela B. Schmider,Roy J. Soberman,Antoine Besnard,Mark P. Jedrychowski,Hyeonwoo Kim,Hua Tu,Eunhee Kim,Se Hoon Choi,Rudolph E. Tanzi,Bruce M. Spiegelman,Christiane D. Wrann +23 more
TL;DR: The authors showed that irisin, the cleaved and circulating form of the exercise-induced membrane protein FNDC5, is sufficient to confer the benefits of exercise on cognitive function.
Journal ArticleDOI
In vitro and in vivo efficacy of a potent opioid receptor agonist, biphalin, compared to subtype-selective opioid receptor agonists for stroke treatment
TL;DR: In vitro and in vivo studies indicate that the nonselective opioid agonist, biphalin, achieves enhanced neuroprotective potency compared to any of the selective opioid agonists, evidenced by reduced edema and infarct ratios.
Journal ArticleDOI
Treadmill Exercise Suppresses Cognitive Decline and Increases White Matter Oligodendrocyte Precursor Cells in a Mouse Model of Prolonged Cerebral Hypoperfusion.
Ryo Ohtomo,Keita Kinoshita,Gaku Ohtomo,Hajime Takase,Gen Hamanaka,Kazuo Washida,Mohammad Rashedul Islam,Christiane D. Wrann,Hiroshi Katsuki,Atsushi Iwata,Josephine Lok,Eng H. Lo,Ken Arai +12 more
TL;DR: This study examines how treadmill exercise changes the cognitive function and white matter cellular pathology in a mouse model of SIVD and establishes a model and cellular foundation for investigating the mechanisms through which exercise preserves cognitive function in SivD.
Journal ArticleDOI
Enkephalin-Fentanyl Multifunctional Opioids as Potential Neuroprotectants for Ischemic Stroke Treatment.
Mohammad Rashedul Islam,Li Yang,Yeon Sun Lee,Victor J. Hruby,Vardan T. Karamyan,Thomas J. Abbruscato +5 more
TL;DR: The results of this study suggest that the multifunctional fluorinated enkephalin analog, LYS739 can be considered as a potential lead for ischemic stroke research and may provide advantages given the multimeric peptide-opiate structure.
Book ChapterDOI
The Role of FNDC5/Irisin in the Nervous System and as a Mediator for Beneficial Effects of Exercise on the Brain
TL;DR: This review will focus on FNDC5 and its secreted form “irisin,” a newly discovered myokine, its role in the nervous system and its therapeutic potential, and the role of other exercise-induced myokines in positive brain effects.