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Angela B. Schmider
Researcher at Harvard University
Publications - 12
Citations - 386
Angela B. Schmider is an academic researcher from Harvard University. The author has contributed to research in topics: Integrin & Cell adhesion molecule. The author has an hindex of 6, co-authored 12 publications receiving 219 citations.
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Journal ArticleDOI
CD177 modulates human neutrophil migration through activation-mediated integrin and chemoreceptor regulation.
Ming Bai,Ricardo Grieshaber-Bouyer,Jun-Xia Wang,Angela B. Schmider,Zachary S. Wilson,Liling Zeng,Olha Halyabar,Olha Halyabar,Matthew D. Godin,Hung N. Nguyen,Anaïs Levescot,Pierre Cunin,Craig T. Lefort,Roy J. Soberman,Peter A. Nigrovic,Peter A. Nigrovic +15 more
TL;DR: It is concluded that CD177 signals in a β2 integrin-dependent manner to orchestrate a set of activation-mediated mechanisms that impair human neutrophil migration.
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Exercise hormone irisin is a critical regulator of cognitive function.
Mohammad Rashedul Islam,Sophia Valaris,Michael F. Young,Erin B. Haley,Renhao Luo,Sabrina F. Bond,Sabrina F. Bond,Sofia Mazuera,Sofia Mazuera,Robert R. Kitchen,Barbara J. Caldarone,Luis E.B. Bettio,Brian R. Christie,Angela B. Schmider,Roy J. Soberman,Antoine Besnard,Mark P. Jedrychowski,Hyeonwoo Kim,Hua Tu,Eunhee Kim,Se Hoon Choi,Rudolph E. Tanzi,Bruce M. Spiegelman,Christiane D. Wrann +23 more
TL;DR: The authors showed that irisin, the cleaved and circulating form of the exercise-induced membrane protein FNDC5, is sufficient to confer the benefits of exercise on cognitive function.
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Coordinated regulation of bidirectional COPI transport at the Golgi by CDC42
TL;DR: It is shown that the coat protein I (COPI) complex sorts anterograde cargoes into these tubules in human cells and that bidirectional COPI transport is modulated by environmental cues through CDC42.
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CD47 plays a critical role in T-cell recruitment by regulation of LFA-1 and VLA-4 integrin adhesive functions
Veronica Azcutia,Matthew Routledge,Marcie R. Williams,Marcie R. Williams,Gail Newton,William A. Frazier,Andre Manica,Kevin Croce,Kevin Croce,Charles A. Parkos,Angela B. Schmider,Melissa V. Turman,Roy J. Soberman,Francis W. Luscinskas,Francis W. Luscinskas +14 more
TL;DR: CD47 associates in cis with T-cell L FA-1 integrins and regulates expression of high-affinity conformations of both LFA-1 and VLA-4 in mice models of innate and adaptive immune responses.
Journal ArticleDOI
Diabetes regulates fructose absorption through thioredoxin-interacting protein
James R Dotimas,James R Dotimas,Austin Lee,Austin Lee,Angela B. Schmider,Shannon H. Carroll,Shannon H. Carroll,Anu Shah,Anu Shah,Julide Bilen,Julide Bilen,Kayla R Elliott,Kayla R Elliott,Ronald B Myers,Ronald B Myers,Roy J. Soberman,Jun Yoshioka,Jun Yoshioka,Richard T. Lee,Richard T. Lee +19 more
TL;DR: It is demonstrated that thioredoxin-interacting protein (Txnip), which regulates glucose homeostasis in mammals, binds to fructose transporters and promotes fructose absorption by the small intestine, and that a diabetic state can promote fructose uptake.