M
Mohammed El Mzibri
Publications - 75
Citations - 793
Mohammed El Mzibri is an academic researcher. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 14, co-authored 46 publications receiving 565 citations.
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Journal ArticleDOI
Role of H2O2 in RET/PTC1 Chromosomal Rearrangement Produced by Ionizing Radiation in Human Thyroid Cells
Rabii Ameziane-El-Hassani,Myriem Boufraqech,Myriem Boufraqech,Odile Lagente-Chevallier,Odile Lagente-Chevallier,Urbain Weyemi,Monique Talbot,Monique Talbot,Didier Métivier,Didier Métivier,Françoise Courtin,Françoise Courtin,Jean Michel Bidart,Jean Michel Bidart,Mohammed El Mzibri,Martin Schlumberger,Martin Schlumberger,Corinne Dupuy,Corinne Dupuy +18 more
TL;DR: This study shows for the first time that H(2)O(2), generated during a 5 Gy X-ray irradiation, causes DNA double-strand breaks and contributes to RET/PTC1 formation in thyroid cells and highlights that oxidative stress could be responsible for the occurrence of RET/ PTC1 rearrangement found in thyroid lesions even in the absence of radiation exposure.
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NADPH Oxidase NOX4 Is a Critical Mediator of BRAFV600E-Induced Downregulation of the Sodium/Iodide Symporter in Papillary Thyroid Carcinomas
Naima Azouzi,Jérémy Cailloux,Jérémy Cailloux,Jérémy Cailloux,Juliana Cazarin,Jeffrey A. Knauf,Jennifer R. Cracchiolo,Abir Al Ghuzlan,Abir Al Ghuzlan,Abir Al Ghuzlan,Dana M. Hartl,Michel Polak,Aurore Carré,Mohammed El Mzibri,Abdelkarim Filali-Maltouf,Abderrahmane Al Bouzidi,Martin Schlumberger,Martin Schlumberger,Martin Schlumberger,James A. Fagin,Rabii Ameziane-El-Hassani,Rabii Ameziane-El-Hassani,Corinne Dupuy,Corinne Dupuy,Corinne Dupuy +24 more
TL;DR: It is shown that NOX4 upregulation is controlled at the transcriptional level by the oncogene via the TGF-β/Smad3 signaling pathway, suggestive of a potential role in BRAFV600E-induced thyroid tumors.
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Antioxidant and Antiproliferative Activities of Bioactive Compounds Contained in Rosmarinus officinalis Used in the Mediterranean Diet
Mohammed Bourhia,Fatima Ezzahra Laasri,Hind Aourik,Aicha Boukhris,Riaz Ullah,Ahmed Bari,Syed Saeed Ali,Mohammed El Mzibri,Laila Benbacer,Said Gmouh +9 more
TL;DR: In the current work, carnosol and carnosic acid exhibit antioxidant and antiproliferative activities in a concentration-dependent manner.
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Breast Cancer in Morocco: A Literature Review
Meriem Slaoui,Rachid Razine,Azeddine Ibrahimi,Mohammed Attaleb,Mohammed El Mzibri,Mariam Amrani +5 more
TL;DR: The genetic and molecular profile of Moroccan patients with breast cancer is established and some new markers for detection and prediction of breast cancer prognosis are proposed.
Journal ArticleDOI
Évaluation de la contamination par les éléments-traces métalliques dans une zone minière du Maroc oriental *
Abdelaziz Smouni,Mohammed Ater,Florence Auguy,Laurent Laplaze,Mohammed El Mzibri,Fatiha Berhada,Abdelkarim Filali-Maltouf,Patrick Doumas +7 more
TL;DR: Une analyse des especes vegetales qui se developpent sur ces zones polluees est envisagee dans le cadre de the mise en place d'un programme de phytoremediation.