M
Molly E. McCue
Researcher at University of Minnesota
Publications - 103
Citations - 3831
Molly E. McCue is an academic researcher from University of Minnesota. The author has contributed to research in topics: Population & Myopathy. The author has an hindex of 28, co-authored 98 publications receiving 3083 citations. Previous affiliations of Molly E. McCue include Kansas State University.
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Journal ArticleDOI
Mutations in DMRT3 affect locomotion in horses and spinal circuit function in mice
Lisa S. Andersson,Martin Larhammar,Fatima Memic,Hanna Wootz,Doreen Schwochow,Carl-Johan Rubin,Kalicharan Patra,Thorvaldur Árnason,Lisbeth Wellbring,Göran Hjälm,Freyja Imsland,Jessica L. Petersen,Molly E. McCue,James R. Mickelson,Gus Cothran,Nadav Ahituv,Lars Roepstorff,Sofia Mikko,Anna Vallstedt,Gabriella Lindgren,Leif Andersson,Leif Andersson,Klas Kullander +22 more
TL;DR: This work shows that a premature stop codon in the DMRT3 gene has a major effect on the pattern of locomotion in horses, and positions Dmrt3 in a pivotal role for configuring the spinal circuits controlling stride in vertebrates.
Journal ArticleDOI
Characterization of ancient and modern genomes by SNP detection and phylogenomic and metagenomic analysis using PALEOMIX
Mikkel Schubert,Luca Ermini,Clio Der Sarkissian,Hakon Jonsson,Aurélien Ginolhac,Robert J. Schaefer,Michael D. Martin,Ruth Fernández,Martin Kircher,Molly E. McCue,Eske Willerslev,Ludovic Orlando +11 more
TL;DR: A flexible and user-friendly pipeline applicable to both modern and ancient genomes, which largely automates the in silico analyses behind whole-genome resequencing and allows for a series of potential applications in paleogenomics, comparative genomics and metagenomics.
Journal ArticleDOI
A High Density SNP Array for the Domestic Horse and Extant Perissodactyla: Utility for Association Mapping, Genetic Diversity, and Phylogeny Studies
Molly E. McCue,Danika L. Bannasch,Jessica L. Petersen,Jessica Gurr,E. Bailey,Matthew M. Binns,Ottmar Distl,Gérard Guérin,Telhisa Hasegawa,Emmeline W. Hill,Tosso Leeb,Gabriella Lindgren,M. Cecilia T. Penedo,Knut Røed,Oliver A. Ryder,June E Swinburne,Teruaki Tozaki,Stephanie J. Valberg,Mark Vaudin,Kerstin Lindblad-Toh,Kerstin Lindblad-Toh,Claire M. Wade,James R. Mickelson +22 more
TL;DR: The results demonstrate the high quality of this SNP genotyping resource, its usefulness in diverse genome analyses of the horse, and potential use in related species.
Journal ArticleDOI
Genome-Wide Analysis Reveals Selection for Important Traits in Domestic Horse Breeds
Jessica L. Petersen,James R. Mickelson,Aaron Rendahl,Stephanie J. Valberg,Lisa S. Andersson,Jeanette Axelsson,E. Bailey,Danika L. Bannasch,Matthew M. Binns,Alexandre Secorun Borges,Pieter A.J. Brama,Artur da Câmara Machado,Stefano Capomaccio,Katia Cappelli,E. Gus Cothran,Ottmar Distl,Laura Y Fox-Clipsham,K. T. Graves,Gérard Guérin,Bianca Haase,Telhisa Hasegawa,Karin Hemmann,Emmeline W. Hill,Tosso Leeb,Gabriella Lindgren,Hannes Lohi,M. S. Lopes,Beatrice A. McGivney,Sofia Mikko,Nick Orr,M. Cecilia T. Penedo,Richard J. Piercy,Marja Raekallio,Stefan Rieder,Knut Røed,June E Swinburne,Teruaki Tozaki,Mark Vaudin,Claire M. Wade,Molly E. McCue +39 more
TL;DR: This work provides further evidence of the importance of MSTN in racing breeds, provides strong evidence for selection upon gait and size, and illustrates the potential for population-based techniques to find genomic regions driving important phenotypes in the modern horse.
Journal ArticleDOI
Genetic diversity in the modern horse illustrated from genome-wide SNP data
Jessica L. Petersen,James R. Mickelson,E. Gus Cothran,Lisa S. Andersson,Jeanette Axelsson,E. Bailey,Danika L. Bannasch,Matthew M. Binns,Alexandre Secorun Borges,Pieter A.J. Brama,Artur da Câmara Machado,Ottmar Distl,Michela Felicetti,Laura Y Fox-Clipsham,K. T. Graves,Gérard Guérin,Bianca Haase,Telhisa Hasegawa,Karin Hemmann,Emmeline W. Hill,Tosso Leeb,Gabriella Lindgren,Hannes Lohi,M. S. Lopes,Beatrice A. McGivney,Sofia Mikko,Nick Orr,M. Cecilia T. Penedo,Richard J. Piercy,Marja Raekallio,Stefan Rieder,Knut Røed,Maurizio Silvestrelli,June E Swinburne,Teruaki Tozaki,Mark Vaudin,Claire M. Wade,Molly E. McCue +37 more
TL;DR: The use of a genome-wide set of autosomal SNPs and 814 horses from 36 breeds to provide the first detailed description of equine breed diversity is described, providing new insights into the relationships among and the diversity within breeds of horses.