M
Morgan Sarrut
Researcher at University of Lyon
Publications - 10
Citations - 310
Morgan Sarrut is an academic researcher from University of Lyon. The author has contributed to research in topics: Hydrophilic interaction chromatography & Supercritical fluid chromatography. The author has an hindex of 6, co-authored 10 publications receiving 248 citations.
Papers
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Journal ArticleDOI
An Online Four-Dimensional HIC×SEC-IM×MS Methodology for Proof-of-Concept Characterization of Antibody Drug Conjugates
Anthony Ehkirch,Valentina D'Atri,Florent Rouvière,Oscar Hernandez-Alba,Alexandre Goyon,Olivier Colas,Morgan Sarrut,Alain Beck,Davy Guillarme,Sabine Heinisch,Sarah Cianférani +10 more
TL;DR: An innovative multidimensional analytical approach combining comprehensive online two-dimensional (2D)-chromatography that consists of HIC and size-exclusion chromatography (SEC), to ion mobility and mass spectrometry (IM-MS) for performing analytical characterization of ADCs under nondenaturing conditions is presented.
Journal ArticleDOI
Optimization of conditions in on-line comprehensive two-dimensional reversed phase liquid chromatography. Experimental comparison with one-dimensional reversed phase liquid chromatography for the separation of peptides
TL;DR: A procedure for RPLC×RPLC separations able to define, for a given analysis time, the optimized LC×LC parameters for achieving the best compromise between high peak capacity and low dilution is proposed.
Journal ArticleDOI
Potential and limitations of on-line comprehensive reversed phase liquid chromatography×supercritical fluid chromatography for the separation of neutral compounds: An approach to separate an aqueous extract of bio-oil
Morgan Sarrut,Amélie Corgier,Gérard Crétier,Agnès Le Masle,Stephané P. A. Dubant,Sabine Heinisch +5 more
TL;DR: RPLCxSFC appears to be a promising alternative to RPLCxRPLC for the separation of complex samples of neutral compounds and may balance for lesser peak efficiency obtained with SFC as second dimension.
Journal ArticleDOI
First inter-laboratory study of a Supercritical Fluid Chromatography method for the determination of pharmaceutical impurities.
Amandine Dispas,Roland Djang’eing’a Marini,Vincent Desfontaine,Jean-Luc Veuthey,Dorina Kotoni,Luca Gioacchino Losacco,Adrian Clarke,Charlene Galea,Debby Mangelings,Brandon M. Jocher,Erik L. Regalado,Katerina Plachka,Lucie Nováková,Benjamin Wuyts,Isabelle François,Michael J. Gray,Andrew J. Aubin,Abhijit Tarafder,Maxime Cazes,Christophe Desvignes,Loic Villemet,Morgan Sarrut,Adrien Raimbault,Elise Lemasson,Eric Lesellier,Caroline West,Tomas Leek,Mengling Wong,Lulu Dai,Kelly Zhang,Alexandre Grand-Guillaume Perrenoud,Claudio Brunelli,Philippe Hennig,Sophie Bertin,Fabien Mauge,Nathalie Da Costa,William Farrell,Madeleine Hill,Niranjan Desphande,Manish Grangrade,Santosh Sadaphule,Ravi Yadav,Sandesh Rane,Shankar Shringare,Marion Iguiniz,Sabine Heinisch,Julien Lefevre,Estelle Corbel,Nicolas Roques,Yvan Vander Heyden,Davy Guillarme,Philippe Hubert +51 more
TL;DR: An inter‐laboratory study was conducted and published for the first time in SFC to assess method reproducibility, and evaluate whether this chromatographic technique could become a reference method for quality control (QC) laboratories.
Journal ArticleDOI
Theoretical and practical interest in UHPLC technology for 2D-LC
TL;DR: In this paper, the authors present some recent applications involving UHPLC in LC x LC, such as food analysis, life sciences, bioenergy and polymers, covering a wide range of analytical fields.