M
Moritz Bosse Biskup
Researcher at Karlsruhe Institute of Technology
Publications - 12
Citations - 632
Moritz Bosse Biskup is an academic researcher from Karlsruhe Institute of Technology. The author has contributed to research in topics: Bioconjugation & Serine. The author has an hindex of 8, co-authored 12 publications receiving 525 citations. Previous affiliations of Moritz Bosse Biskup include Scripps Research Institute & University of Konstanz.
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Journal ArticleDOI
Bioconjugation via azide-Staudinger ligation: an overview.
TL;DR: Bioconjugation techniques using organic azides are compared in this critical review of chemical ligation reactions and their application to chemical biology.
Journal ArticleDOI
Chemical Synthesis of Glycosaminoglycans.
Marco Mende,Christin Bednarek,Mirella Wawryszyn,Paul F. Sauter,Moritz Bosse Biskup,Ute Schepers,Stefan Bräse +6 more
TL;DR: This Review summarizes the progress of chemical syntheses of GAGs over the last 10 years and discusses novel glycosylation strategies, elongation sequences, and protecting group patterns of synthesized or isolated G AGs.
Journal ArticleDOI
Genetic code expansion for multiprotein complex engineering
Christine Koehler,Paul F. Sauter,Mirella Wawryszyn,Gemma Estrada Girona,Kapil Gupta,Jonathan J M Landry,Markus Hsi-Yang Fritz,Ksenija Radic,Jan Erik Hoffmann,Zhuo Angel Chen,Juan Zou,Piau Siong Tan,Bence Galik,Sini Junttila,Peggy Stolt-Bergner,Giancarlo Pruneri,Attila Gyenesei,Carsten Schultz,Moritz Bosse Biskup,Hueseyin Besir,Vladimir Benes,Juri Rappsilber,Juri Rappsilber,Martin Jechlinger,Jan O. Korbel,Imre Berger,Imre Berger,Stefan Braese,Edward A. Lemke +28 more
TL;DR: The versatility of this efficient and robust protein production platform, 'MultiBacTAG', is demonstrated for the fluorescent labeling of target proteins and biologics using click chemistries, for glycoengineering of antibodies, and for structure–function studies of novel eukaryotic complexes.
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Synthesis-guided structure revision of the sarcodonin, sarcoviolin, and hydnellin natural product family.
TL;DR: A sweeping structural revision of the sarcodonin natural product family is proposed after extensive studies aimed at their chemical synthesis, including replacement of the N,N-dioxide moiety with an oxime, ring-opening of the central diketopiperazine, and transposition of the terphenyl wing.
Journal ArticleDOI
TGFβ counteracts LYVE-1-mediated induction of lymphangiogenesis by small hyaluronan oligosaccharides.
Jochen Bauer,Melanie Rothley,Melanie Rothley,Anja Schmaus,Anja Schmaus,Luca Quagliata,Markus Sebastian Ehret,Moritz Bosse Biskup,Véronique Orian-Rousseau,David A. Jackson,Ronald J. Pettis,Alfred Harvey,Stefan Bräse,Wilko Thiele,Wilko Thiele,Jonathan P. Sleeman,Jonathan P. Sleeman +16 more
TL;DR: The effects of sHA on the lymphatic endothelium are investigated, finding that in contrast to high-molecular-weight HA, sHA of 4–25 disaccharides in length can promote the proliferation of LECs and lymphangiogenesis in a manner that is dependent on their size and concentration.