M
Moying Yin
Researcher at University of Cincinnati Academic Health Center
Publications - 16
Citations - 4890
Moying Yin is an academic researcher from University of Cincinnati Academic Health Center. The author has contributed to research in topics: Transforming growth factor beta & DNA damage. The author has an hindex of 14, co-authored 16 publications receiving 4736 citations. Previous affiliations of Moying Yin include University of Cincinnati.
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Journal ArticleDOI
Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease
Marcia M. Shull,Ilona Ormsby,Ann B. Kier,Sharon A. Pawlowski,Ronald J. Diebold,Moying Yin,Ruth D. Allen,Charles L. Sidman,Gabriele Proetzel,Dawn Calvin,Nikki Annunziata,Thomas Doetschman +11 more
TL;DR: TGF-β1-deficient mice may be valuable models for human immune and inflammatory disorders, including autoimmune diseases, transplant rejection and graft versus host reactions.
Journal ArticleDOI
Transforming growth factor-β3 is required for secondary palate fusion
Gabriele Proetzel,Sharon A. Pawlowski,Michael V. Wiles,Moying Yin,Gregory P. Boivin,Philip N. Howles,Jixang Ding,Mark W. J. Ferguson,Thomas Doetschman +8 more
TL;DR: This result demonstrates that TGF–β3 affects palatal shelf fusion by an intrinsic, primary mechanism rather than by effects secondary to craniofacial defects.
Journal ArticleDOI
Fibroblast growth factor 2 control of vascular tone.
Ming Zhou,Roy L. Sutliff,Richard J. Paul,John N. Lorenz,James B. Hoying,Christian C. Haudenschild,Moying Yin,J. Douglas Coffin,Ling Kong,Evangelia G. Kranias,Wusheng Luo,Gregory P. Boivin,John J. Duffy,Sharon A. Pawlowski,Thomas Doetschman +14 more
TL;DR: It is shown that a well-known growth factor, FCF2, long thought to be involved in many developmental and homeostatic processes, including growth of the tissue layers of vessel walls, functions in vascular tone control.
Journal ArticleDOI
Early-onset multifocal inflammation in the transforming growth factor beta 1-null mouse is lymphocyte mediated.
Ronald J. Diebold,Michael J. Eis,Moying Yin,Ilona Ormsby,Greg P. Boivin,Bruce J. Darrow,Jeffrey E. Saffitz,Thomas Doetschman +7 more
TL;DR: It is shown that cardiac cells are hyperproliferative and that intercellular adhesion molecule 1 (ICAM-1) is elevated, revealing a vital role for TGF beta 1 in regulating lymphocyte proliferation and activation, which contribute to the maintenance of self tolerance.
Journal ArticleDOI
TGF-β1 Regulates Lymphocyte Homeostasis by Preventing Activation and Subsequent Apoptosis of Peripheral Lymphocytes
Ramireddy Bommireddy,Vijay Saxena,Ilona Ormsby,Moying Yin,Gregory P. Boivin,George F. Babcock,George F. Babcock,Ram Singh,Thomas Doetschman +8 more
TL;DR: It is demonstrated that unlike wild-type splenic lymphocytes, those from Tgfb1−/− mice are hyporesponsive to receptor-mediated mitogenic stimulation, as evidenced by diminished proliferation and reduced IL-2 production, and they have elevated levels of IFN-γ and eventually undergo apoptosis.