M
Mui Hoon Nai
Researcher at National University of Singapore
Publications - 30
Citations - 857
Mui Hoon Nai is an academic researcher from National University of Singapore. The author has contributed to research in topics: Ultimate tensile strength & Nanocomposite. The author has an hindex of 12, co-authored 30 publications receiving 591 citations. Previous affiliations of Mui Hoon Nai include STMicroelectronics & Nanyang Technological University.
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Journal ArticleDOI
Epithelial bridges maintain tissue integrity during collective cell migration
Sri Ram Krishna Vedula,Sri Ram Krishna Vedula,Hiroaki Hirata,Mui Hoon Nai,Agustí Brugués,Yusuke Toyama,Xavier Trepat,Chwee Teck Lim,Benoit Ladoux,Benoit Ladoux +9 more
TL;DR: It is shown that monolayers of human keratinocytes migrating along functionalized micropatterned surfaces comprising alternating strips of extracellular matrix (fibronectin) and non-adherent polymer form suspended multicellular bridges over the non- adherent areas.
Journal ArticleDOI
Potassium channel dysfunction in human neuronal models of Angelman syndrome
Alfred Xuyang Sun,Qiang Yuan,Masahiro Fukuda,Weonjin Yu,Haidun Yan,Grace Lim,Mui Hoon Nai,Giuseppe D'Agostino,Hoang-Dai Tran,Yoko Itahana,Danlei Wang,Hidayat Lokman,Koji Itahana,Stephanie Wai Lin Lim,Jiong Tang,Ya Yin Chang,Menglan Zhang,Stuart A. Cook,Owen J. L. Rackham,Chwee Teck Lim,Eng-King Tan,Huck-Hui Ng,Kah-Leong Lim,Kah-Leong Lim,Yong-hui Jiang,Hyunsoo Shawn Je +25 more
TL;DR: It is demonstrated that UBE3A suppresses neuronal hyperexcitability via ubiquitin-mediated degradation of calcium- and voltage-dependent big potassium (BK) channels, suggesting that BK channelopathy underlies epilepsy in AS and support the use of human cells to model human developmental diseases.
Journal ArticleDOI
Interface tailoring to enhance mechanical properties of carbon nanotube reinforced magnesium composites
Mui Hoon Nai,Jun Wei,Manoj Gupta +2 more
TL;DR: In this paper, the use of a metallic coating of nanoscale thickness on carbon nanotube to enhance the interfacial characteristics in carbon-nanotube reinforced magnesium (Mg) composites is discussed.
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Development of high performance Mg–TiO2 nanocomposites targeting for biomedical/structural applications
TL;DR: In this paper, near dense low volume fraction of Mg-TiO2 nanocomposites are synthesized using disintegrated melt deposition technique followed by hot extrusion, and microstructural characterization of the nanocomposition reveal significant reduction in grain size of pure magnesium with addition of titanium dioxide with a maximum of ∼47% reduction with 2.5 vol.% nano addition.
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Thermal-Disrupting Interface Mitigates Intercellular Cohesion Loss for Accurate Topical Antibacterial Therapy.
Benhui Hu,Benhui Hu,Christopher Berkey,Timothy Joel Feliciano,Xiaohong Chen,Zhuyun Li,Chao Chen,Shahrouz Amini,Mui Hoon Nai,Qun Li Lei,Ran Ni,Juan Wang,Wan Ru Leow,Shaowu Pan,Yong Qiang Li,Pingqiang Cai,Ali Miserez,Shuzhou Li,Chwee Teck Lim,Yun-Long Wu,Teri W. Odom,Reinhold H. Dauskardt,Xiaodong Chen +22 more
TL;DR: A localized thermal managing strategy, thermal‐disrupting interface induced mitigation (TRIM), is reported, to minimize intercellular cohesion loss for accurate antibacterial therapy.