Julia L. Drewes

TL;DR: The Human Tumor Atlas Network (HTAN), part of the NCI Cancer Moonshot Initiative, will establish a clinical, experimental, computational, and organizational framework to generate informative and accessible three-dimensional atlases of cancer transitions for a diverse set of tumor types.

TL;DR: Researchers in the USA and Malaysia found that bowel cancers were enriched in invasive bacterial biofilms as well as several specific gut and oral species, including one - Fusobacterium nucleatum - known to promote tumorigenesis in mouse models.

TL;DR: Recent advances in understanding of the contributions of the microbiota to prevention, initiation/progression, and treatment of colorectal cancer are discussed, with a major focus on biofilms and the antimicrobial and antitumoural immune response.

TL;DR: The results indicate that maternal inflammation shunts tryptophan metabolism away from the serotonin to the kynurenine pathway, which may lead to excitotoxic injury along with impaired development of serotonin-mediated thalamocortical fibers in the newborn brain.

TL;DR: This review aims to highlight what is known about biofilm formation and in vivo models available for the biofilm study and critique the contribution of biofilms to human diseases, focusing on the lung diseases, cystic fibrosis and chronic obstructive pulmonary disease, and the gut diseases, inflammatory bowel disease and colorectal cancer.