M
Muni Grainger
Researcher at National Institute for Medical Research
Publications - 4
Citations - 1510
Muni Grainger is an academic researcher from National Institute for Medical Research. The author has contributed to research in topics: Plasmodium falciparum & Subtilisin. The author has an hindex of 4, co-authored 4 publications receiving 1458 citations.
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Journal ArticleDOI
Discovery of Gene Function by Expression Profiling of the Malaria Parasite Life Cycle
Karine G. Le Roch,Yingyao Zhou,Peter L. Blair,Muni Grainger,J. Kathleen Moch,J. David Haynes,Patricia de la Vega,Anthony A. Holder,Serge Batalov,Daniel J. Carucci,Elizabeth A. Winzeler,Elizabeth A. Winzeler +11 more
TL;DR: A high-density oligonucleotide array is used to generate expression profiles of human and mosquito stages of the malaria parasite's life cycle and finds genes with highly correlated levels and temporal patterns of expression were often involved in similar functions or cellular processes.
Journal ArticleDOI
A subtilisin-like protein in secretory organelles of Plasmodium falciparum merozoites.
Michael J. Blackman,Hisashi Fujioka,William Stafford,Mohammed Sajid,Barbara Clough,S. L. Fleck,Masamichi Aikawa,Muni Grainger,Fiona Hackett +8 more
TL;DR: The subcellular location and timing of secretion of p47 suggest that it is likely to play a role in erythrocyte invasion, and PfSUB-1 is a new potential target for antimalarial drug development.
Journal ArticleDOI
PfSUB-2: a second subtilisin-like protein in Plasmodium falciparum merozoites.
TL;DR: The identification of a second P. falciparum subtilisin-like merozoite protein, called PfSUB-2, which is encoded by a single copy gene and expressed as a large putative type I integral membrane protein which undergoes extensive post-translational processing.