Murlidhar S. Shingare

TL;DR: In this article, a one-pot synthesis of polyhydroquinoline derivatives using nanosized Nickel (Ni) as a heterogeneous catalyst has been proposed, which has promising features for the reaction response such as the shortest reaction time, excellent product yields, simple work-up procedure, and purification of products by non-chromatographic methods.

TL;DR: In this paper, a stability indicating reversed-phase HPLC method has been developed and subsequently validated for simultaneous estimation of amlodipine (AM) present as AM besylate (AB), and benazepril hydrochloride (BH) from their combination product.

TL;DR: In this paper, the condensation reaction of 4-oxo-(4H)-1-benzopyran-3-carbaldehydes and of aromatic aldehydes with 3-methyl-1-phenylpyrazolin-5-4H-one were carried out in an ionic liquid, ethylammonium nitrate, at room temperature in shorter times with higher yields of 78−92 and 70−75%, respectively, than found using conventional procedures.

TL;DR: In vitro antimicrobial activities of the synthesized compounds were investigated against Gram-positive Bacillus subtilis, Gram-negative Escherichia coli and fungi Candida albicans and Aspergillus niger and some of the tested compounds showed significant antimicrobial activity.

TL;DR: Synthesis of new 2-chloro-3-((4-phenyl-1H-1,2, 3-triazol-1-yl)methyl)quinoline derivatives (4a-h) using 1,3-dipolar cycloaddition (click chemistry) has been achieved in very high yield.