N
N. E. White
Researcher at Imperial College London
Publications - 10
Citations - 795
N. E. White is an academic researcher from Imperial College London. The author has contributed to research in topics: Relaxin-3 & Relaxin. The author has an hindex of 8, co-authored 10 publications receiving 776 citations.
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Journal ArticleDOI
Post-embryonic ablation of AgRP neurons in mice leads to a lean, hypophagic phenotype
Gavin A. Bewick,James Gardiner,Waljit S. Dhillo,Aysha Kent,N. E. White,Zoe Webster,Mohammad A. Ghatei,Stephen R. Bloom +7 more
TL;DR: The data suggest that postembryonic partial loss of AgRP/NPY neurons leads to a lean, hypophagic phenotype in mice with targeted deletion of either NPY or AgRP or both.
Journal ArticleDOI
Central relaxin-3 administration causes hyperphagia in male Wistar rats.
Barbara McGowan,Sarah Stanley,Kirsty L. Smith,N. E. White,M M Connolly,Emily L. Thompson,James Gardiner,Kevin Murphy,M. A. Ghatei,S.R. Bloom +9 more
TL;DR: In this article, the effect of central administration of relaxin-3 on food intake in male Wistar rats was investigated and the receptor involved in mediating these effects was also investigated.
Central Relaxin-3 administration causes hyperphagia in male Wistar rats
Barbara McGowan,Sarah Stanley,Kirsty L. Smith,N. E. White,M M Connolly,James Gardiner,M. A. Ghatei,S.R. Bloom +7 more
TL;DR: A novel role for relaxin-3 in appetite regulation is suggested after it was found that intra-PVN H3 administration significantly increased 1-h food intake in satiated rats in the early light phase and the early dark phase.
Journal ArticleDOI
Ghrelin stimulates insulin-induced glucose uptake in adipocytes.
A.D. Patel,Sarah Stanley,Kevin G. Murphy,Gary Frost,James Gardiner,Aysha Kent,N. E. White,M. A. Ghatei,Stephen R. Bloom +8 more
TL;DR: Ghrelin appears to directly potentiate adipocyte insulin-stimulated glucose uptake in selective adipocyte populations and may play a role in adipocyte regulation of glucose homeostasis.
Journal ArticleDOI
Hypothalamic mapping of orexigenic action and Fos-like immunoreactivity following relaxin-3 administration in male Wistar rats
Barbara McGowan,Sarah Stanley,N. E. White,Anna Spångeus,Michael Patterson,Emily L. Thompson,Kirsty L. Smith,Joe Donovan,James Gardiner,M. A. Ghatei,Stephen R. Bloom +10 more
TL;DR: Two studies provide additional support for relaxin-3 as an important peptide in appetite regulation by mapping the hypothalamic site(s) of the orexigenic action of relaxin -3 and examining the site(S) of neuronal activation following central relaxin)-3 administration.