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N. Lynn Henry
Researcher at University of Michigan
Publications - 181
Citations - 8590
N. Lynn Henry is an academic researcher from University of Michigan. The author has contributed to research in topics: Breast cancer & Medicine. The author has an hindex of 35, co-authored 140 publications receiving 6821 citations. Previous affiliations of N. Lynn Henry include National Institutes of Health & University of North Carolina at Chapel Hill.
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Journal ArticleDOI
Assessment of Ki67 in Breast Cancer: Recommendations from the International Ki67 in Breast Cancer Working Group
Mitch Dowsett,Torsten O. Nielsen,Roger A'Hern,John M. S. Bartlett,R. Charles Coombes,Jack Cuzick,Matthew J. Ellis,N. Lynn Henry,Judith Hugh,Tracy Lively,Lisa M. McShane,Soon Paik,Frédérique Penault-Llorca,Ljudmila Prudkin,Meredith M. Regan,Janine Salter,Christos Sotiriou,Ian E. Smith,Giuseppe Viale,Jo Anne Zujewski,Daniel F. Hayes +20 more
TL;DR: Comprehensive recommendations on preanalytical and analytical assessment, and interpretation and scoring of Ki67 were formulated based on current evidence, geared toward achieving a harmonized methodology, create greater between-laboratory and between-study comparability, and allow earlier valid applications of this marker in clinical practice.
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American Cancer Society/American Society of Clinical Oncology Breast Cancer Survivorship Care Guideline
Carolyn D. Runowicz,Corinne R. Leach,N. Lynn Henry,Karen S. Henry,Heather T. Mackey,Rebecca Cowens-Alvarado,Rachel S. Cannady,Mandi Pratt-Chapman,Stephen B. Edge,Linda A. Jacobs,Arti Hurria,Lawrence B. Marks,Samuel J. LaMonte,Ellen Warner,Gary H. Lyman,Patricia A. Ganz +15 more
TL;DR: Recommendations on surveillance for breast cancer recurrence, screening for second primary cancers, assessment and management of physical and psychosocial long-term and late effects of breast cancer and its treatment, health promotion, and care coordination/practice implications are made.
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Breast Cancer Follow-Up and Management After Primary Treatment: American Society of Clinical Oncology Clinical Practice Guideline Update
James Khatcheressian,Patricia Hurley,Elissa T. Bantug,Laura J. Esserman,Eva Grunfeld,Francine E. Halberg,Alexander Hantel,N. Lynn Henry,Hyman B. Muss,Thomas J. Smith,Victor G. Vogel,Antonio C. Wolff,Mark R. Somerfield,Nancy E. Davidson +13 more
TL;DR: The Update Committee concluded that no revisions to the existing ASCO recommendations were warranted and recommended regular history, physical examination, and mammography for breast cancer follow-up.
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Activation of an IL6 Inflammatory Loop Mediates Trastuzumab Resistance in HER2+ Breast Cancer by Expanding the Cancer Stem Cell Population
Hasan Korkaya,Gwang Il Kim,April Davis,Fayaz Malik,N. Lynn Henry,Suthinee Ithimakin,Ahmed A. Quraishi,Nader Tawakkol,Rosemarie C. D'Angelo,Amanda K. Paulson,Susan Chung,Tahra Luther,Hayley J. Paholak,Suling Liu,Khaled A. Hassan,Qin Zen,Shawn G. Clouthier,Max S. Wicha +17 more
TL;DR: It is demonstrated that trastuzumab resistance may be mediated by an IL6 inflammatory loop and suggested that blocking this loop may provide alternative strategy to overcometrastuzuab resistance.
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Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK
TL;DR: It is shown that human CAK possesses the CTD kinase activity characteristic of TFIIH, which is homologous to human MO15 and cyclin H, which form the cyclin-dependent kinase-activating kinase (CAK).