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N P Day
Researcher at Mahidol University
Publications - 27
Citations - 1384
N P Day is an academic researcher from Mahidol University. The author has contributed to research in topics: Malaria & Artesunate. The author has an hindex of 16, co-authored 25 publications receiving 1319 citations. Previous affiliations of N P Day include Churchill Hospital & John Radcliffe Hospital.
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Journal ArticleDOI
Fake antimalarials in Southeast Asia are a major impediment to malaria control: multinational cross‐sectional survey on the prevalence of fake antimalarials
Arjen M. Dondorp,Paul N. Newton,Paul N. Newton,Mayfong Mayxay,W. Van Damme,Frank Smithuis,Shunmay Yeung,Shunmay Yeung,A. Petit,Antony J. Lynam,Arlyne Johnson,Tran Tinh Hien,Rose McGready,Jj J. Farrar,Jj J. Farrar,Sornchai Looareesuwan,N P Day,N P Day,Michael D. Green,Nicholas J. White,Nicholas J. White +20 more
TL;DR: This study aims to assess the prevalence of counterfeit antimalarial drugs in Southeast (SE) Asia and to establish a database of known and suspected counterfeit drugs in the region.
Journal ArticleDOI
Direct In Vivo Assessment of Microcirculatory Dysfunction in Severe Falciparum Malaria
Arjen M. Dondorp,Arjen M. Dondorp,Can Ince,Prakaykaew Charunwatthana,Josh Hanson,A. van Kuijen,M. A. Faiz,M. R. Rahman,Mahtabuddin Hasan,E Bin Yunus,A. Ghose,Ronnatrai Ruangveerayut,Direk Limmathurotsakul,Keshen R. Mathura,Nicholas J. White,Nicholas J. White,N P Day,N P Day +17 more
TL;DR: Patients with severe falciparum malaria show extensive microvascular obstruction that is proportional to the severity of the disease, which underscores the prominent role that microVascular obstruction plays in the pathophysiology of severe malaria and illustrates the fundamental difference between the microv vascular pathophysiological of malaria and that of bacterial sepsis.
Journal ArticleDOI
Pathophysiologic and prognostic role of cytokines in dengue hemorrhagic fever
Delia Bethell,K Flobbe,X T Cao,N P Day,T P Pham,W. A. Buurman,M J Cardosa,N J White,Dominic P. Kwiatkowski +8 more
TL;DR: Plasma cytokine concentrations were prospectively studied in 443 Vietnamese children with DHF and large-scale release of soluble TNFR may be an early and specific marker of the endothelial changes that cause dengue shock syndrome.
Journal ArticleDOI
CISH and Susceptibility to Infectious Diseases
Chiea Chuen Khor,Fredrik O. Vannberg,Stephen J Chapman,Hailong Guo,Sunny H. Wong,Andrew Walley,Damjan Vukcevic,Anna Rautanen,Tara C. Mills,Chang K-C.,Kam K-M.,Amelia C. Crampin,Bagrey Ngwira,Leung C-C.,Tam C-M.,Chan C-Y.,Sung Jjy.,Yew W-W.,Toh K-Y.,Tay Skh.,Dominic P. Kwiatkowski,Christian Lienhardt,Hien T-T.,N P Day,N Peshu,Kevin Marsh,Kathryn Maitland,J A Scott,Thomas N. Williams,James A. Berkley,Sian Floyd,Tang Nls.,Fine Pem.,Goh Dlm.,Hill Avs. +34 more
TL;DR: Variants of CISH are associated with susceptibility to diseases caused by diverse infectious pathogens, suggesting that negative regulators of cytokine signaling have a role in immunity against various infectious diseases.
Journal ArticleDOI
Population Pharmacokinetics of Piperaquine after Two Different Treatment Regimens with Dihydroartemisinin-Piperaquine in Patients with Plasmodium falciparum Malaria in Thailand
Joel Tarning,Joel Tarning,Elizabeth A. Ashley,Niklas Lindegardh,Niklas Lindegardh,Kasia Stepniewska,Kasia Stepniewska,Lucy Phaiphun,N P Day,N P Day,Rose McGready,Rose McGready,Michael Ashton,F Nosten,F Nosten,N J White,N J White +16 more
TL;DR: The data lend further support to a simplified once-daily treatment regimen to improve treatment adherence and efficacy and indicate that weight-adjusted piperaquine doses in children may need to be higher than in adults.