Nana Jin

TL;DR: Analyzing optical genome maps of 154 individuals from the 26 populations sequenced in the 1000 Genomes Project, it is found that phylogenetic population patterns of large SVs are similar to those of single nucleotide variations in 86% of the human genome, while ~2% ofThe genome has high structural complexity.

TL;DR: The findings suggest that TFEB exerts anti-inflammatory effects in diabetic mice and such function in ECs is achieved by inhibiting IKK activity and increasing I&kgr;B&agr; level to suppress NF-&kGr;B activity.

TL;DR: Evidence is provided that female fish exposed to hypoxia exhibit reproductive impairments (follicle atresia and retarded oocyte development), leading to a drastic reduction in hatching success in the F2 generation of the transgenerational group, although they have never been exposed to Hypoxia.

TL;DR: OMTools is an efficient and intuitive data processing and visualization suite to handle and explore large‐scale optical mapping profiles and form an accessible and convenient pipeline for optical mapping analyses.

TL;DR: The differential transcriptome patterns in blood are not representative of those in endometrium, and the blood transcriptome cannot differentiate among the women with RIF, RM or fertile.