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Nasha Qiu
Researcher at Zhejiang University
Publications - 24
Citations - 2039
Nasha Qiu is an academic researcher from Zhejiang University. The author has contributed to research in topics: Gene delivery & Transfection. The author has an hindex of 10, co-authored 21 publications receiving 1269 citations. Previous affiliations of Nasha Qiu include University of North Carolina at Chapel Hill & Center for Excellence in Education.
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Journal ArticleDOI
Rational Design of Cancer Nanomedicine: Nanoproperty Integration and Synchronization.
TL;DR: The typical cancer‐drug‐delivery process of an intravenously administered nanomedicine is analyzed and it is concluded that the delivery involves a five‐step CAPIR cascade and that high efficiency at every step is critical to guarantee high overall therapeutic efficiency.
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Precise nanomedicine for intelligent therapy of cancer
Huabing Chen,Zhanjun Gu,An Hongwei,An Hongwei,Chunying Chen,Chunying Chen,Jie Chen,Jie Chen,Ran Cui,Siqin Chen,Wei-Hai Chen,Xuesi Chen,Xuesi Chen,Xiaoyuan Chen,Zhuo Chen,Baoquan Ding,Qian Dong,Qin Fan,Ting Fu,Da-Yong Hou,Qiao Jiang,Hengte Ke,Xiqun Jiang,Gang Liu,Suping Li,Tianyu Li,Zhuang Liu,Guangjun Nie,Muhammad Ovais,Muhammad Ovais,Dai-Wen Pang,Nasha Qiu,Youqing Shen,Huayu Tian,Huayu Tian,Chao Wang,Hao Wang,Zi-Qi Wang,Huaping Xu,Jiang Fei Xu,Xiangliang Yang,Shuang Zhu,Xianchuang Zheng,Xian-Zheng Zhang,Yanbing Zhao,Weihong Tan,Weihong Tan,Xi Zhang,Yuliang Zhao +48 more
TL;DR: The recent advances of intelligent cancer nanomedicine are demonstrated, and the comprehensive understanding of their structure-function relationship for smart and efficient cancer nanotechine including various imaging and therapeutic applications, as well as nanotoxicity is discussed.
Journal ArticleDOI
Nonviral cancer gene therapy: Delivery cascade and vector nanoproperty integration.
Zhuxian Zhou,Xiangrui Liu,Dingcheng Zhu,Yue Wang,Zhen Zhang,Xuefei Zhou,Nasha Qiu,Xuesi Chen,Youqing Shen +8 more
TL;DR: This review analyzes the cancer gene‐delivery cascade and the barriers, the needed nanopro properties and the current strategies for overcoming these barriers, and outlines PEGylation, surface‐charge, size, and stability dilemmas in vector nanoproperties to efficiently accomplish the cancer genes delivery cascade.
Journal ArticleDOI
Esterase-Activated Charge-Reversal Polymer for Fibroblast-Exempt Cancer Gene Therapy.
Nasha Qiu,Xiangrui Liu,Yin Zhong,Zhuxian Zhou,Ying Piao,Lei Miao,Qianzhi Zhang,Jianbin Tang,Leaf Huang,Youqing Shen +9 more
TL;DR: An esterase-responsive charge-reversal polymer mediates selective gene expression in the cancer cells high in esterases over fibroblasts low in Esterase activity, enabling potent cancer gene therapy with few side effects.
Journal ArticleDOI
Tumor extravasation and infiltration as barriers of nanomedicine for high efficacy: The current status and transcytosis strategy.
Quan Zhou,Chengyuan Dong,Wufa Fan,Haiping Jiang,Jiajia Xiang,Nasha Qiu,Ying Piao,Tao Xie,Yingwu Luo,Zi-Chen Li,Fusheng Liu,Youqing Shen +11 more
TL;DR: Using nanocarriers to induce transcytosis of endothelial and cancer cells to enable nanomedicines to actively extravasate into and infiltrate in solid tumors, which led to radically increased anticancer activity.