D
Dingcheng Zhu
Researcher at University of Hamburg
Publications - 28
Citations - 1307
Dingcheng Zhu is an academic researcher from University of Hamburg. The author has contributed to research in topics: Gene delivery & Transfection. The author has an hindex of 12, co-authored 26 publications receiving 909 citations. Previous affiliations of Dingcheng Zhu include Zhejiang University & Hangzhou Normal University.
Papers
More filters
Journal ArticleDOI
Nonviral cancer gene therapy: Delivery cascade and vector nanoproperty integration.
Zhuxian Zhou,Xiangrui Liu,Dingcheng Zhu,Yue Wang,Zhen Zhang,Xuefei Zhou,Nasha Qiu,Xuesi Chen,Youqing Shen +8 more
TL;DR: This review analyzes the cancer gene‐delivery cascade and the barriers, the needed nanopro properties and the current strategies for overcoming these barriers, and outlines PEGylation, surface‐charge, size, and stability dilemmas in vector nanoproperties to efficiently accomplish the cancer genes delivery cascade.
Journal ArticleDOI
Fusogenic Reactive Oxygen Species Triggered Charge-Reversal Vector for Effective Gene Delivery
Xin Liu,Jiajia Xiang,Dingcheng Zhu,Liming Jiang,Zhuxian Zhou,Jianbin Tang,Xiangrui Liu,Yongzhuo Huang,Youqing Shen +8 more
TL;DR: A novel fusogenic lipidic polyplex (FLPP) vector is designed to fuse with cell membranes, mimicking viropexis, and eject the polyplex into the cytosol, where the cationic polymer is subsequently oxidized by intracellular reactive oxygen species and converts to being negatively charged, efficiently releasing DNA.
Journal ArticleDOI
The Future of Layer-by-Layer Assembly: A Tribute to ACS Nano Associate Editor Helmuth Möhwald
Shuang Zhao,Frank Caruso,Lars Dähne,Gero Decher,Gero Decher,Bruno G. De Geest,Jinchen Fan,Neus Feliu,Yury Gogotsi,Paula T. Hammond,Mark C. Hersam,Ali Khademhosseini,Nicholas A. Kotov,Stefano Leporatti,Yan Li,Fred Lisdat,Luis M. Liz-Marzán,Sergio Moya,Paul Mulvaney,Andrey L. Rogach,Sathi Roy,Dmitry G. Shchukin,Andre G. Skirtach,Molly M. Stevens,Gleb B. Sukhorukov,Paul S. Weiss,Zhao Yue,Dingcheng Zhu,Wolfgang J. Parak +28 more
TL;DR: The developments and applications that are to come in LbL assembly, focusing on coatings, bulk materials, membranes, nanocomposites, and delivery vehicles, are discussed.
Journal ArticleDOI
Intracellularly Disintegratable Polysulfoniums for Efficient Gene Delivery
Dingcheng Zhu,Huijie Yan,Xin Liu,Jiajia Xiang,Zhuxian Zhou,Jianbin Tang,Xiangrui Liu,Youqing Shen +7 more
TL;DR: A new class of polysulfoniums that can degrade into neutral thioether fragments triggered by reactive oxygen species (ROS) is reported, which have excellent serum resistance and efficiently deliver the suicide gene pTRAIL to intraperitoneal tumors eliciting effective anticancer activity.
Journal ArticleDOI
The Inductive Effect of Bone Morphogenetic protein-4 on Chondral-Lineage Differentiation and in Situ Cartilage Repair
Yangzi Jiang,Long Kun Chen,Dingcheng Zhu,Guo Rong Zhang,Chao Guo,Yi Ying Qi,Hongwei Ouyang,Hongwei Ouyang +7 more
TL;DR: BMP-4 is more potent than BMP-7 for cartilage differentiation, as evidenced by higher expression of type II collagen and aggrecan genes and lower Young's modulus in group III, which indicates the mechanical properties of the repaired tissue.