Natalya P. Bondar

TL;DR: The hypothesis that brief separation of pups from their mothers (handling), which can be considered as moderate stress, may result in future positive changes in behavior is supported.

TL;DR: It has been shown that mRNA levels of the Tph2, Maoa, Sert, Htr1a, Bdnf, and Creb genes in the raphe nuclei of defeated mice are decreased as compared with the controls, and period of relative rest is not enough for most serotonergic genes to recover expression to the control levels.

TL;DR: This mini-review focuses on the structure and regulation of the Bbnf gene as well as on the stress–BDNF interactions under early-life adverse conditions.

TL;DR: The results indicate that extended positive fighting experience in a social conflict heightens aggression, increases proliferation of neuronal progenitors and production of young neurons in the hippocampus, and decreases neuronal activity in the amygdala; these changes can be modified by depriving winners of the opportunity for further fights.

TL;DR: The data show that the development of depression under social stress conditions is correlated with suppression of the overactive molecular response to induced stress, involving gene regulatory resistance to glucocorticoid molecules, potentially via a chromatin remodeling mechanism.