T
Tatyana V. Michurina
Researcher at Stony Brook University
Publications - 26
Citations - 5144
Tatyana V. Michurina is an academic researcher from Stony Brook University. The author has contributed to research in topics: Stem cell & Progenitor cell. The author has an hindex of 17, co-authored 24 publications receiving 4587 citations. Previous affiliations of Tatyana V. Michurina include Moscow Institute of Physics and Technology & Cold Spring Harbor Laboratory.
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Journal ArticleDOI
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
Simón Méndez-Ferrer,Tatyana V. Michurina,Francesca Ferraro,Amin R. Mazloom,Ben D. MacArthur,Ben D. MacArthur,Sergio A. Lira,David T. Scadden,Avi Ma'ayan,Grigori Enikolopov,Paul S. Frenette,Paul S. Frenette +11 more
TL;DR: It is demonstrated that mesenchymal stem cells (MSCs), identified using nestin expression, constitute an essential HSC niche component and are indicative of a unique niche in the bone marrow made of heterotypic stem-cell pairs.
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Division-Coupled Astrocytic Differentiation and Age-Related Depletion of Neural Stem Cells in the Adult Hippocampus
Juan M. Encinas,Tatyana V. Michurina,Natalia Peunova,June Hee Park,Julie Tordo,Daniel A. Peterson,Gordon Fishell,Alex Koulakov,Grigori Enikolopov +8 more
TL;DR: A scheme of the neurogenesis cascade in the adult hippocampus is presented that includes a proposed "disposable stem cell" model and accounts for the disappearance of hippocampal neural stem cells, the appearance of new astrocytes, and the age-related decline in the production of new neurons.
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Ovarian surface epithelium at the junction area contains a cancer-prone stem cell niche
Andrea Flesken-Nikitin,Chang-Il Hwang,Chieh-Yang Cheng,Tatyana V. Michurina,Tatyana V. Michurina,Grigori Enikolopov,Grigori Enikolopov,Alexander Yu. Nikitin +7 more
TL;DR: The hilum cells of the ovarian surface epithelium show increased transformation potential after inactivation of tumour suppressor genes Trp53 and Rb1, whose pathways are altered frequently in the most aggressive and common type of human EOC, high-grade serous adenocarcinoma.
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Genetic approaches identify adult pituitary stem cells
Anatoli S. Gleiberman,Tatyana V. Michurina,Juan M. Encinas,Jose L. Roig,Peter Krasnov,Francesca Balordi,Gord Fishell,Michael G. Rosenfeld,Grigori Enikolopov +8 more
TL;DR: A different stem cell strategy for tissue maintenance, distinct from that observed for dedicated or facultative stem cells, is described, which generates a mosaic organ with two phenotypically similar subsets of endocrine cells that have different origins and different life histories.
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ΔNp63α Is an Oncogene that Targets Chromatin Remodeler Lsh to Drive Skin Stem Cell Proliferation and Tumorigenesis
William M. Keyes,Matteo Pecoraro,Victoria Aranda,Emma Vernersson-Lindahl,Wangzhi Li,Hannes Vogel,Xuecui Guo,Elvin L. Garcia,Tatyana V. Michurina,Grigori Enikolopov,Senthil K. Muthuswamy,Senthil K. Muthuswamy,Alea A. Mills +12 more
TL;DR: It is indicated that ΔNp63α is an oncogene that cooperates with Ras to promote tumor-initiating stem-like proliferation and suggest that Lsh-mediated chromatin-remodeling events are critical to this process.